Protein Information

Cytoscape View


UniProt AC / UniProt ID P36871 / PGM1_HUMAN
Protein Name Phosphoglucomutase-1
Gene Name Name: PGM1
Organism Homo sapiens (Human)

PRO ID PR:P36871
DAG View
PRO Name phosphoglucomutase-1 (human)
Definition A phosphoglucomutase-1 that is encoded in the genome of human.
Short Label hPGM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P36871 (PGM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K8 Ubiquitination PhosphoSitePlus
Y12 Phosphorylation PhosphoSitePlus
K16 Acetylation PhosphoSitePlus   UniProt 19608861
K16 Ubiquitination PhosphoSitePlus
T19 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
Y66 Phosphorylation PhosphoSitePlus
T115 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S117 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18669648, 25288802, ...19690332, 20068231
S134 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y195 Phosphorylation PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus   UniProt 24275569
S206 Phosphorylation PhosphoSitePlus   UniProt 24275569
K219 Acetylation PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
R293 Methylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
R343 Methylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
Y353 Phosphorylation PhosphoSitePlus
T355 Phosphorylation PhosphoSitePlus
T357 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus   UniProt 24275569
S408 Phosphorylation PhosphoSitePlus
K419 Acetylation PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
Y430 Phosphorylation PhosphoSitePlus
R452 Methylation PhosphoSitePlus
K457 Acetylation PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
T467 Phosphorylation Q16512 (PKN1) , Q13153 (PAK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 15378030
K470 Ubiquitination PhosphoSitePlus
Y476 Phosphorylation PhosphoSitePlus
R491 Methylation PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus   UniProt 24275569
T507 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus   UniProt 24275569
T513 Phosphorylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
Y521 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T19 Phosphorylation HPRD 20166139
T115 Phosphorylation HPRD 18212344, 20058876, 19651622, ...18510355, 18669648, 20166139, 20068231, 17924679
S117 Phosphorylation HPRD 17081983, 18767875, 20058876, ...18452278, 19651622, 18669648, 20166139, 19415658, 20068231, 17924679
Y353 Phosphorylation HPRD 20068231
S369 Phosphorylation HPRD 20068231
S505 Phosphorylation HPRD 20166139
T507 Phosphorylation HPRD 20166139
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
T133 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K146 * Biomuta DOID:11934 / head and neck cancer [ tcga ]
K146 T146 Biomuta DOID:363 / uterine cancer [ tcga ]
S201 I201 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K349 T349 Biomuta DOID:363 / uterine cancer [ tcga ]
T355 A355 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K419 N419 Biomuta DOID:3571 / liver cancer [ icgc ]
R491 H491 Biomuta DOID:363 / uterine cancer [ tcga ]
R491 C491 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T495 I495 Biomuta DOID:2394 / ovarian cancer [ tcga ]