iPTMnet Report for P36871 (PGM1)
Protein Information
UniProt AC / UniProt ID | P36871 / PGM1_HUMAN |
Protein Name | Phosphoglucomutase-1 |
Gene Name | Name: PGM1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P36871 |
PRO Name | phosphoglucomutase-1 (human) |
Definition | A phosphoglucomutase-1 that is encoded in the genome of human. |
Short Label | hPGM1 |
Category | organism-gene |
P36871 (PGM1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 21406692, 22814378 | ||
K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y12 | Phosphorylation | score1 | PhosphoSitePlus | |||
K16 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K16 | Ubiquitination | score1 | PhosphoSitePlus | |||
T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y66 | Phosphorylation | score1 | PhosphoSitePlus | |||
T115 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S117 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 18669648, 25288802, ... | ||
S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
K172 | Ubiquitination | score1 | PhosphoSitePlus | |||
T185 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
Y195 | Phosphorylation | score1 | PhosphoSitePlus | |||
T197 | Phosphorylation | score1 | PhosphoSitePlus | |||
S201 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S206 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K219 | Acetylation | score1 | PhosphoSitePlus | |||
Y232 | Phosphorylation | score1 | PhosphoSitePlus | |||
S247 | Phosphorylation | score1 | PhosphoSitePlus | |||
R293 | Methylation | score1 | PhosphoSitePlus | |||
S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
R343 | Methylation | score1 | PhosphoSitePlus | |||
S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
T348 | Phosphorylation | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y353 | Phosphorylation | score1 | PhosphoSitePlus | |||
T355 | Phosphorylation | score1 | PhosphoSitePlus | |||
T357 | Phosphorylation | score1 | PhosphoSitePlus | |||
S369 | Phosphorylation | score1 | PhosphoSitePlus | |||
S378 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S408 | Phosphorylation | score1 | PhosphoSitePlus | |||
K419 | Acetylation | score1 | PhosphoSitePlus | |||
K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y430 | Phosphorylation | score1 | PhosphoSitePlus | |||
R452 | Methylation | score1 | PhosphoSitePlus | |||
K457 | Acetylation | score1 | PhosphoSitePlus | |||
K457 | Ubiquitination | score1 | PhosphoSitePlus | |||
T467 | Phosphorylation | Q16512 (PKN1) , Q13153 (PAK1) | score3 | neXtProt phospho.ELM PhosphoSitePlus Signor UniProt | 15378030 | |
K470 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y476 | Phosphorylation | score1 | PhosphoSitePlus | |||
R491 | Methylation | score1 | PhosphoSitePlus | |||
T495 | Phosphorylation | score1 | PhosphoSitePlus | |||
S505 | O-Glycosylation | score1 | GlyGen | 16408927, 26374642, 34725712, ... | ||
S505 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T507 | Phosphorylation | score1 | PhosphoSitePlus | |||
S509 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T513 | Phosphorylation | score1 | PhosphoSitePlus | |||
S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y521 | Phosphorylation | score1 | PhosphoSitePlus | |||
S541 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T19 | Phosphorylation | score0 | HPRD | 20166139 | ||
T115 | Phosphorylation | score0 | HPRD | 18212344, 20058876, 19651622, ... | ||
S117 | Phosphorylation | score0 | HPRD | 17081983, 18767875, 20058876, ... | ||
Y353 | Phosphorylation | score0 | HPRD | 20068231 | ||
S369 | Phosphorylation | score0 | HPRD | 20068231 | ||
S505 | Phosphorylation | score0 | HPRD | 20166139 | ||
T507 | Phosphorylation | score0 | HPRD | 20166139 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
T133 | Phosphorylation | score1 | PhosphoSitePlus | |||
S135 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K146 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K146 | T146 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S201 | I201 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S206 | I206 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S247 | L247 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
R343 | W343 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
K349 | T349 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T355 | A355 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
R452 | C452 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
R491 | H491 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
R491 | C491 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
Y521 | F521 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S541 | F541 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |