iPTMnet Report for P35900 (KRT20)
Protein Information
UniProt AC / UniProt ID | P35900 / K1C20_HUMAN |
Protein Name | Keratin, type I cytoskeletal 20 |
Gene Name | Name: KRT20 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P35900 |
PRO Name | keratin, type I cytoskeletal 20 (human) |
Definition | A keratin, type I cytoskeletal 20 that is encoded in the genome of human. |
Short Label | hKRT20 |
Category | organism-gene |
P35900 (KRT20) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
S13 | Phosphorylation | P17252 (PRKCA) , P49137 (MAPKAPK2) | score4 | neXtProt PhosphoSitePlus RLIMS-P UniProt | 16608857, 20724476 | |
S34 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 16083285 | ||
Y36 | Phosphorylation | score1 | PhosphoSitePlus | |||
R42 | Methylation | score1 | PhosphoSitePlus | |||
R45 | Methylation | score1 | PhosphoSitePlus | |||
Y84 | Phosphorylation | score1 | PhosphoSitePlus | |||
S94 | Phosphorylation | score0 | HPRD | 20068231 | ||
S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y120 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y121 | Phosphorylation | score1 | PhosphoSitePlus | |||
K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
T168 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
T369 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y370 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y384 | Phosphorylation | score1 | PhosphoSitePlus | |||
S387 | Phosphorylation | score1 | PhosphoSitePlus | |||
T402 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S11 | R11 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
R42 | Q42 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
R42 | W42 | Biomuta | [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
R45 | H45 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
R45 | C45 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic ] | |
K149 | E149 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
Y370 | C370 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S387 | R387 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |