iPTMnet Report for P35611 (ADD1)
Protein Information
UniProt AC / UniProt ID | P35611 / ADDA_HUMAN |
Protein Name | Alpha-adducin |
Gene Name | Name: ADD1 Synonyms:ADDA; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P35611 |
PRO Name | alpha-adducin (human) |
Definition | An alpha-adducin that is encoded in the genome of human. |
Short Label | hADD1 |
Category | organism-gene |
P35611 (ADD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
S5 | Phosphorylation | score3 | phospho.ELM | 15611095, 16116087, 8810272, ... | ||
T11 | Phosphorylation | score1 | PhosphoSitePlus | |||
S12 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 29925526, 21406692, 23186163, ... | ||
S12 | Phosphorylation | P06493 (CDK1) | score2 | PhosphoSitePlus | 24379415 | |
T16 | Phosphorylation | score1 | PhosphoSitePlus | |||
K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y24 | Phosphorylation | score1 | PhosphoSitePlus | |||
R27 | Methylation | score1 | PhosphoSitePlus | |||
Y35 | Phosphorylation | score1 | PhosphoSitePlus | |||
K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
S59 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 24275569, 8810272 | ||
S64 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K140 | Acetylation | score1 | PhosphoSitePlus | |||
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
K143 | Ubiquitination | score1 | PhosphoSitePlus | |||
K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
K288 | Ubiquitination | score1 | PhosphoSitePlus | |||
T331 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S334 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
K348 | Ubiquitination | score1 | PhosphoSitePlus | |||
S353 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17287340, 23186163 | ||
S355 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 29925526, 24379415, 23186163, ... | ||
S355 | Phosphorylation | P06493 (CDK1) | score2 | PhosphoSitePlus | 24379415 | |
S358 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 17287340, 15302935, ... | ||
T364 | Phosphorylation | score1 | PhosphoSitePlus | |||
S366 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
Y393 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y395 | Phosphorylation | score1 | PhosphoSitePlus | |||
K406 | Ubiquitination | score1 | PhosphoSitePlus | |||
S408 | Phosphorylation | score3 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 8810272 | ||
S408 | Phosphorylation | P17612 (PRKACA) | score2 | neXtProt | 8810272 | |
S423 | Phosphorylation | score1 | PhosphoSitePlus | |||
S427 | Phosphorylation | score1 | PhosphoSitePlus | |||
T429 | Phosphorylation | score1 | PhosphoSitePlus | |||
S431 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S436 | Phosphorylation | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 18669648, 17081983, 8810272 | ||
S436 | Phosphorylation | P17612 (PRKACA) | score2 | neXtProt | 8810272 | |
K439 | Ubiquitination | score1 | PhosphoSitePlus | |||
T445 | Phosphorylation | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 10209029, 10947843, 15910744 | ||
T445 | Phosphorylation | O75116 (ROCK2) | score2 | neXtProt | 10209029 | |
T445 | Phosphorylation | Q13464 (ROCK1) | score3 | phospho.ELM PhosphoSitePlus Signor | 10209029 | |
T445 | Phosphorylation | Q9Y5S2 (CDC42BPB) | score2 | neXtProt | 10947843 | |
S457 | Phosphorylation | score1 | PhosphoSitePlus | |||
S464 | Phosphorylation | score1 | PhosphoSitePlus | |||
S465 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 17287340, 17081983, ... | ||
T480 | Phosphorylation | score3 | neXtProt phospho.ELM PhosphoSitePlus Signor UniProt | 10209029 | ||
T480 | Phosphorylation | O75116 (ROCK2) | score2 | neXtProt | 10209029 | |
T480 | Phosphorylation | Q13464 (ROCK1) | score3 | PhosphoSitePlus Signor | 10209029 | |
S481 | Phosphorylation | score3 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 8810272 | ||
S481 | Phosphorylation | P17612 (PRKACA) | score2 | neXtProt | 8810272 | |
T482 | Phosphorylation | score1 | PhosphoSitePlus | |||
S483 | Phosphorylation | score1 | PhosphoSitePlus | |||
K515 | Ubiquitination | score1 | PhosphoSitePlus | |||
S521 | O-Glycosylation | score1 | GlyGen | 23301498, 35008409, 34725712, ... | ||
C525 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
R531 | Methylation | score1 | PhosphoSitePlus | |||
S532 | Phosphorylation | score1 | PhosphoSitePlus | |||
T540 | O-Glycosylation | score1 | GlyGen | 23301498, 35008409, 34725712, ... | ||
S542 | O-Glycosylation | score1 | GlyGen | 23301498, 35008409, 34725712, ... | ||
Y550 | Phosphorylation | score1 | PhosphoSitePlus | |||
S557 | O-Glycosylation | score1 | GlyGen | 23301498, 35008409, 34725712, ... | ||
T558 | O-Glycosylation | score1 | GlyGen | 23301498, 35008409, 34725712, ... | ||
T559 | O-Glycosylation | score1 | GlyGen | 23301498, 35008409, 34725712, ... | ||
T559 | Phosphorylation | score1 | PhosphoSitePlus | |||
T565 | O-Glycosylation | score1 | GlyGen | 23301498, 35008409, 34725712, ... | ||
T568 | O-Glycosylation | score1 | GlyGen | 23301498, 35008409, 34725712, ... | ||
Y575 | Phosphorylation | score1 | PhosphoSitePlus | |||
S586 | Phosphorylation | score1 | PhosphoSitePlus | |||
S600 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S613 | Phosphorylation | score1 | PhosphoSitePlus | 18847512 | ||
S613 | Phosphorylation | P24941 (CDK2) | score1 | PhosphoSitePlus | 18847512 | |
T614 | Phosphorylation | score1 | PhosphoSitePlus | 18847512 | ||
T614 | Phosphorylation | P24941 (CDK2) | score1 | PhosphoSitePlus | 18847512 | |
S645 | Phosphorylation | score1 | PhosphoSitePlus | |||
S669 | Phosphorylation | score1 | PhosphoSitePlus | |||
T671 | Phosphorylation | score1 | PhosphoSitePlus | |||
S678 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S707 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 17081983, 24275569 | ||
S710 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 17081983 | ||
S714 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S716 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 17081983, 24711455, 24275569, ... | ||
S716 | Phosphorylation | P17252 (PRKCA) | score3 | PhosphoSitePlus | 24711455, 9679146 | |
T724 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31548578 | ||
S726 | Phosphorylation | score4 | IEDB neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 29925526, 32897882, 17081983, ... | ||
S726 | Phosphorylation | O14757 (CHEK1) | score1 | PhosphoSitePlus | 21851590 | |
S726 | Phosphorylation | P17252 (PRKCA) | score4 | PhosphoSitePlus Signor | 16116087, 8810272, 12743105, ... | |
S726 | Phosphorylation | P17612 (PRKACA) | score2 | neXtProt | 8810272 | |
S726 | Phosphorylation | Q05513 (PRKCZ) | score4 | PhosphoSitePlus Signor | 15611095, 8810272, 9679146 | |
S726 | Phosphorylation | Q05655 (PRKCD) | score2 | PhosphoSitePlus | 17341583 | |
S731 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 32897882 | ||
S735 | Phosphorylation | score1 | PhosphoSitePlus | |||
S737 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T11 | Phosphorylation | score0 | HPRD | 20068231 | ||
S12 | Phosphorylation | score0 | HPRD | 18088087, 18767875, 19664995, ... | ||
T331 | Phosphorylation | score0 | HPRD | 18669648 | ||
S334 | Phosphorylation | score0 | HPRD | 18669648 | ||
S353 | Phosphorylation | score0 | HPRD | 17287340, 19664995, 20068231 | ||
S355 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 20058876, ... | ||
S358 | Phosphorylation | score0 | HPRD | 19413330, 18510355, 18491316, ... | ||
T364 | Phosphorylation | score0 | HPRD | 20068231 | ||
S366 | Phosphorylation | score0 | HPRD | 18669648, 19664994 | ||
S408 | Phosphorylation | score1 | HPRD | 8810272 | ||
S408 | Phosphorylation | P17612 (PRKACA) | score1 | HPRD | 8810272 | |
S420 | Phosphorylation | score0 | HPRD | 17081983 | ||
S423 | Phosphorylation | score0 | HPRD | 17081983 | ||
T429 | Phosphorylation | score0 | HPRD | 17081983 | ||
S431 | Phosphorylation | score0 | HPRD | 18669648, 19664995 | ||
S436 | Phosphorylation | score2 | HPRD | 18669648, 8810272 | ||
S436 | Phosphorylation | P17612 (PRKACA) | score2 | HPRD | 18669648, 8810272 | |
T445 | Phosphorylation | score1 | HPRD | 10209029 | ||
T445 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 10209029 | |
S464 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
S465 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 15302935, ... | ||
T480 | Phosphorylation | score1 | HPRD | 10209029 | ||
T480 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 10209029 | |
T482 | Phosphorylation | score0 | HPRD | 20068231 | ||
S586 | Phosphorylation | score0 | HPRD | 19651622 | ||
S600 | Phosphorylation | score0 | HPRD | 18510355 | ||
S613 | Phosphorylation | score0 | HPRD | 17081983 | ||
T614 | Phosphorylation | score0 | HPRD | 17081983 | ||
S669 | Phosphorylation | score0 | HPRD | 17081983 | ||
T675 | Phosphorylation | score0 | HPRD | 17081983 | ||
S695 | Phosphorylation | score2 | HPRD | 8810272, 9679146 | ||
S695 | Phosphorylation | Q05655 (PRKCD) | score2 | HPRD | 8810272, 9679146 | |
S707 | Phosphorylation | score0 | HPRD | 20058876, 17081983 | ||
S710 | Phosphorylation | score0 | HPRD | 17081983 | ||
S716 | Phosphorylation | score0 | HPRD | 17081983 | ||
S726 | Phosphorylation | score0 | HPRD | 19413330 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T11 | Phosphorylation | score0 | HPRD | 20068231 | ||
S12 | Phosphorylation | score0 | HPRD | 18088087, 18767875, 19664995, ... | ||
T331 | Phosphorylation | score0 | HPRD | 18669648 | ||
S334 | Phosphorylation | score0 | HPRD | 18669648 | ||
S353 | Phosphorylation | score0 | HPRD | 17287340, 19664995, 20068231 | ||
S355 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 20058876, ... | ||
S358 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 18491316, ... | ||
T364 | Phosphorylation | score0 | HPRD | 20068231 | ||
S366 | Phosphorylation | score0 | HPRD | 18669648, 19664994 | ||
S408 | Phosphorylation | score1 | HPRD | 8810272 | ||
S408 | Phosphorylation | P17612 (PRKACA) | score1 | HPRD | 8810272 | |
S420 | Phosphorylation | score0 | HPRD | 17081983 | ||
S423 | Phosphorylation | score0 | HPRD | 17081983 | ||
T429 | Phosphorylation | score0 | HPRD | 17081983 | ||
S431 | Phosphorylation | score0 | HPRD | 18669648, 19664995 | ||
S436 | Phosphorylation | score2 | HPRD | 18669648, 8810272 | ||
S436 | Phosphorylation | P17612 (PRKACA) | score2 | HPRD | 18669648, 8810272 | |
T445 | Phosphorylation | score1 | HPRD | 10209029 | ||
T445 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 10209029 | |
S464 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
S465 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 15302935, ... | ||
T480 | Phosphorylation | score1 | HPRD | 10209029 | ||
T480 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 10209029 | |
T482 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y550 | Phosphorylation | score1 | PhosphoSitePlus | |||
S586 | Phosphorylation | score0 | HPRD | 19651622 | ||
S600 | Phosphorylation | score0 | HPRD | 18510355 | ||
S613 | Phosphorylation | score0 | HPRD | 17081983 | ||
T614 | Phosphorylation | score0 | HPRD | 17081983 | ||
Y628 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T11 | Phosphorylation | score0 | HPRD | 20068231 | ||
S12 | Phosphorylation | score0 | HPRD | 18088087, 18767875, 19664995, ... | ||
T331 | Phosphorylation | score0 | HPRD | 18669648 | ||
S334 | Phosphorylation | score0 | HPRD | 18669648 | ||
S353 | Phosphorylation | score0 | HPRD | 17287340, 19664995, 20068231 | ||
S355 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 20058876, ... | ||
S358 | Phosphorylation | score0 | HPRD | 19413330, 18510355, 18491316, ... | ||
T364 | Phosphorylation | score0 | HPRD | 20068231 | ||
S366 | Phosphorylation | score0 | HPRD | 18669648, 19664994 | ||
S408 | Phosphorylation | score1 | HPRD | 8810272 | ||
S408 | Phosphorylation | P17612 (PRKACA) | score1 | HPRD | 8810272 | |
S420 | Phosphorylation | score0 | HPRD | 17081983 | ||
S423 | Phosphorylation | score0 | HPRD | 17081983 | ||
T429 | Phosphorylation | score0 | HPRD | 17081983 | ||
S431 | Phosphorylation | score0 | HPRD | 18669648, 19664995 | ||
S436 | Phosphorylation | score2 | HPRD | 18669648, 8810272 | ||
S436 | Phosphorylation | P17612 (PRKACA) | score2 | HPRD | 18669648, 8810272 | |
T445 | Phosphorylation | score1 | HPRD | 10209029 | ||
T445 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 10209029 | |
S464 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
S465 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 15302935, ... | ||
T511 | Phosphorylation | score1 | HPRD | 10209029 | ||
T511 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 10209029 | |
T513 | Phosphorylation | score0 | HPRD | 20068231 | ||
S617 | Phosphorylation | score0 | HPRD | 19651622 | ||
S631 | Phosphorylation | score0 | HPRD | 18510355 | ||
S644 | Phosphorylation | score0 | HPRD | 17081983 | ||
T645 | Phosphorylation | score0 | HPRD | 17081983 | ||
S700 | Phosphorylation | score0 | HPRD | 17081983 | ||
T706 | Phosphorylation | score0 | HPRD | 17081983 | ||
S726 | Phosphorylation | score2 | HPRD | 8810272, 9679146 | ||
S726 | Phosphorylation | Q05655 (PRKCD) | score2 | HPRD | 8810272, 9679146 | |
S738 | Phosphorylation | score0 | HPRD | 20058876, 17081983 | ||
S741 | Phosphorylation | score0 | HPRD | 17081983 | ||
S747 | Phosphorylation | score0 | HPRD | 17081983 | ||
S757 | Phosphorylation | score0 | HPRD | 19413330 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S557 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T11 | Phosphorylation | score0 | HPRD | 20068231 | ||
S12 | Phosphorylation | score0 | HPRD | 18088087, 18767875, 19664995, ... | ||
T331 | Phosphorylation | score0 | HPRD | 18669648 | ||
S334 | Phosphorylation | score0 | HPRD | 18669648 | ||
S353 | Phosphorylation | score0 | HPRD | 17287340, 19664995, 20068231 | ||
S355 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 20058876, ... | ||
S358 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 18491316, ... | ||
T364 | Phosphorylation | score0 | HPRD | 20068231 | ||
S366 | Phosphorylation | score0 | HPRD | 18669648, 19664994 | ||
S408 | Phosphorylation | score1 | HPRD | 8810272 | ||
S408 | Phosphorylation | P17612 (PRKACA) | score1 | HPRD | 8810272 | |
S420 | Phosphorylation | score0 | HPRD | 17081983 | ||
S423 | Phosphorylation | score0 | HPRD | 17081983 | ||
T429 | Phosphorylation | score0 | HPRD | 17081983 | ||
S431 | Phosphorylation | score0 | HPRD | 18669648, 19664995 | ||
S436 | Phosphorylation | score2 | HPRD | 18669648, 8810272 | ||
S436 | Phosphorylation | P17612 (PRKACA) | score2 | HPRD | 18669648, 8810272 | |
T445 | Phosphorylation | score1 | HPRD | 10209029 | ||
T445 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 10209029 | |
S464 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
S465 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 15302935, ... | ||
T511 | Phosphorylation | score1 | HPRD | 10209029 | ||
T511 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 10209029 | |
T513 | Phosphorylation | score0 | HPRD | 20068231 | ||
S617 | Phosphorylation | score0 | HPRD | 19651622 | ||
S631 | Phosphorylation | score0 | HPRD | 18510355 | ||
S644 | Phosphorylation | score0 | HPRD | 17081983 | ||
T645 | Phosphorylation | score0 | HPRD | 17081983 |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | P35611 (ADD1) | S726 | Q9ULW0 (TPX2) | unknown | eFIP | 29925526 |