iPTMnet Report for P35568 (IRS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P35568 / IRS1_HUMAN
Protein Name Insulin receptor substrate 1
Gene Name Name: IRS1
Organism Homo sapiens (Human)

PRO ID PR:P35568
DAG View
PRO Name insulin receptor substrate 1 (human)
Definition An insulin receptor substrate 1 that is encoded in the genome of human.
Short Label hIRS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35568 (IRS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S3 Phosphorylation HPRD   PhosphoSitePlus 19651622
S7 Phosphorylation PhosphoSitePlus
S24 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 15849359, 16970908, 16574739, ...8349691, 25330241
S24 Phosphorylation P17252 (PRKCA) Signor 16574739
S24 Phosphorylation P53350 (PLK1) phospho.ELM   PhosphoSitePlus   Signor 15849359
S24 Phosphorylation P67870 (CSNK2B) HPRD 8349691
Y46 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15592455, 18083107
Y47 Phosphorylation PhosphoSitePlus
K52 Acetylation PhosphoSitePlus
K61 Acetylation PhosphoSitePlus
Y87 Phosphorylation HPRD   PhosphoSitePlus 20058876
T88 Phosphorylation HPRD 8349691
T88 Phosphorylation P67870 (CSNK2B) HPRD 8349691
S99 Phosphorylation HPRD 8349691
S99 Phosphorylation P67870 (CSNK2B) HPRD 8349691
Y107 Phosphorylation PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
Y183 Phosphorylation PhosphoSitePlus
S268 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 12351658
S268 Phosphorylation O14920 (IKBKB) HPRD 12351658
S270 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12351658, 18077418, 28934129, ...18952604, 19651622, 9312143, 22348058
S270 Phosphorylation O14920 (IKBKB) HPRD 19651622, 18077418, 12351658
S270 Phosphorylation P23443 (RPS6KB1) neXtProt   PhosphoSitePlus   Signor 9312143, 18952604
S270 Phosphorylation Q13535 (ATR) PhosphoSitePlus 18077418
S272 Phosphorylation HPRD   phospho.ELM 12351658
S272 Phosphorylation O14920 (IKBKB) HPRD 12351658
S273 Phosphorylation PhosphoSitePlus
S274 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 12351658
S274 Phosphorylation O14920 (IKBKB) HPRD 12351658
S277 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
T305 Phosphorylation PhosphoSitePlus
S307 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 14697666, 20702573, 12510059, ...17575262, 19897715, 21119656, 24846082, 22348058, 12730242, 22328823, 22266116, 24068326, 14583092, 22728372, 16210322, 15153564, 20594757, 29311680, 20541543, 18952604, 21900690, 23174405, 25645159, 27506476, 25120613, 27222060, 26899161, 20351777, 27936435, 15199052, 18187553, 18372392, 16046301, 31311314, 29177868, 30572687, 27686967, 30240640, 17276034, 23565163, 25355439, 20594161, 26604643, 33723215, 23566306, 17481767, 25799226, 11606564, 23095254, 17077083, 14579029, 28656239, 9335553, 29738527, 31396538, 15802620, 28934129, 23891856, 16754954, 22766331, 18380932, 27544192, 26698173, 29393871, 15516986, 29698741, 12714600, 20587749, 16516141, 20382011, 14641015, 11160134, 15020250, 22046423, 21505982, 16914728, 31137828, 21478152, 16055440, 17095576, 22227580, 26704265, 18496818, 26983645, 23481042, 14556646, 16129690, 30374127, 23958494, 29432553, 15582605, 16839860, 16269459, 19524129, 22491740, 23182460, 12351658, 16099428, 28731188, 18498745, 28790390, 32875583, 19095745, 21786209, 21852229, 23592917, 12409308, 20384568, 28161417, 35656886
S307 Phosphorylation O14920 (IKBKB) HPRD 12351658
S307 Phosphorylation P23443 (RPS6KB1) neXtProt   PhosphoSitePlus   RLIMS-P+ 18952604, 16914728, 23565163
S307 Phosphorylation P42345 (MTOR) Signor 9335553
S307 Phosphorylation P45983 (MAPK8) Signor 14579029, 12510059
S307 Phosphorylation P45984 (MAPK9) Signor 14579029
S307 Phosphorylation Q02750 (MAP2K1) Signor 11160134
S307 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus 15516986, 14583092
T309 Phosphorylation PhosphoSitePlus
T311 Phosphorylation PhosphoSitePlus
S312 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18160431, 15199052, 12510059, ...12351658, 22457223, 17204522, 17360977, 20685959, 22348058, 16505244, 19567513, 16516141, 21589939, 32536688, 15613682, 35833836, 18728222, 27340831, 19501568, 33173197, 14769130, 15952059, 19593406, 20393162, 17242212, 15001544, 18498745, 21252690, 20863384, 10722755, 16284649, 15044323, 15713122, 16960890, 16505239, 11606564, 27207509, 21937042, 17647275, 25580119, 16123357, 21852229, 22862962, 21040800
S312 Phosphorylation O14733 (MAP2K7) Signor 17360977
S312 Phosphorylation O14920 (IKBKB) HPRD   neXtProt   PhosphoSitePlus 12351658, 11606564, 10722755
S312 Phosphorylation P28482 (MAPK1) Signor 17242212
S312 Phosphorylation P45983 (MAPK8) HPRD   neXtProt   PhosphoSitePlus   Signor 12351658, 15001544, 11606564, ...18728222, 10722755
S315 Phosphorylation PhosphoSitePlus   Signor 14579029, 12510059, 9335553
S315 Phosphorylation P45983 (MAPK8) Signor 14579029, 12510059
S315 Phosphorylation P45984 (MAPK9) Signor 9335553
S323 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 16129678, 15516986, 16611834, ...14583092, 24275569, 15069075
S323 Phosphorylation P05771 (PRKCB) PhosphoSitePlus 16611834
S323 Phosphorylation Q05513 (PRKCZ) neXtProt   PhosphoSitePlus   Signor 16129678, 16611834, 15069075
S323 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus   Signor 16611834, 15516986, 14583092, ...15069075
S329 Phosphorylation PhosphoSitePlus
S330 Phosphorylation HPRD   PhosphoSitePlus 8349691
S330 Phosphorylation P67870 (CSNK2B) HPRD 8349691
T335 Phosphorylation PhosphoSitePlus
S337 Phosphorylation RLIMS-P 23669880
S341 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 12351658
S341 Phosphorylation O14920 (IKBKB) HPRD 12351658
S345 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 12351658
S345 Phosphorylation O14920 (IKBKB) HPRD 12351658
S348 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 16020478, 17360977, 19690332, ...18220336
S350 Phosphorylation PhosphoSitePlus
T351 Phosphorylation HPRD   PhosphoSitePlus 19664994
S362 Phosphorylation neXtProt   PhosphoSitePlus 18285345, 14583092
S362 Phosphorylation Q05655 (PRKCD) neXtProt 18285345, 14583092
S372 Phosphorylation PhosphoSitePlus
R373 Methylation PhosphoSitePlus
S374 Phosphorylation phospho.ELM   PhosphoSitePlus 16020478
S383 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus 16611834
S441 Phosphorylation P05771 (PRKCB) PhosphoSitePlus 16611834
S441 Phosphorylation Q05513 (PRKCZ) PhosphoSitePlus 16611834
S441 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus 16611834
S444 Phosphorylation PhosphoSitePlus
T446 Phosphorylation PhosphoSitePlus   RLIMS-P 17360977
S449 Phosphorylation PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus   UniProt 24275569
S463 Phosphorylation PhosphoSitePlus
Y465 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 17827393, 27434075
Y465 Phosphorylation P08069 (IGF1R) Signor 17827393
Y483 Phosphorylation PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus   RLIMS-P 17360977
T498 Phosphorylation PhosphoSitePlus
T502 Phosphorylation HPRD   PhosphoSitePlus 8349691
T502 Phosphorylation P68400 (CSNK2A1) HPRD 8349691
S503 Phosphorylation PhosphoSitePlus
T525 Phosphorylation PhosphoSitePlus
S527 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 19651622, 12351658, 24275569, ...18498745, 16914728
S527 Phosphorylation O14920 (IKBKB) HPRD 19651622, 12351658
S527 Phosphorylation P23443 (RPS6KB1) PhosphoSitePlus   Signor 16914728
T530 Phosphorylation phospho.ELM   PhosphoSitePlus 16020478
S531 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 12351658, 18220336
S531 Phosphorylation O14920 (IKBKB) HPRD 19651622, 12351658
T533 Phosphorylation PhosphoSitePlus
S574 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 15516986, 14583092, 16131083
S574 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus 15516986, 14583092
S581 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
T605 Phosphorylation PhosphoSitePlus
T608 Phosphorylation PhosphoSitePlus
Y612 Phosphorylation HPRD   IntAct   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17827393, 11416002, 28934129, ...30092354, 28414818, 23401856, 12220227, 17902048, 26874193, 28345670, 11162588, 16188907, 20150288, 23460259, 29259227, 17242212, 15001544, 23360399, 21939528, 28161417, 25302072, 23688189, 15044323, 29486856, 28955049, 26297026, 14579029, 18083107, 19762915, 16230374, 21829658, 25886138
Y612 Phosphorylation P08069 (IGF1R) Signor 17827393
Y612 Phosphorylation P23458 (JAK1) HPRD 11162588
Y612 Phosphorylation P45984 (MAPK9) Signor 14579029
S616 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 17360977, 26297026, 17242212, ...21937042, 15001544, 16131083, 17640984, 14769130, 12510059, 9395471, 22476197, 16354680, 15044323, 15143153, 15713122, 8626671
S616 Phosphorylation P27361 (MAPK3) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 9395471, 15001544
S616 Phosphorylation P28482 (MAPK1) HPRD   neXtProt   Signor 9395471, 15001544, 16131083
S616 Phosphorylation P45983 (MAPK8) Signor 12510059
S616 Phosphorylation Q05655 (PRKCD) Signor 15143153
S624 Phosphorylation PhosphoSitePlus
S629 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 17081983, 16131083, 17640984, ...19651622, 24275569
S629 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus 17640984
Y632 Phosphorylation HPRD   IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17827393, 11416002, 28934129, ...30863203, 26077338, 8382612, 7680644, 28414818, 23401856, 15044323, 29698741, 7680095, 8530377, 23404947, 22558377, 15001544, 17640984, 31137828, 31620609, 11162588, 14579029, 18083107, 17279354
Y632 Phosphorylation P08069 (IGF1R) PhosphoSitePlus   Signor 17827393, 8530377
Y632 Phosphorylation P23458 (JAK1) HPRD 11162588
Y632 Phosphorylation P45984 (MAPK9) Signor 14579029
S636 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 25667991, 16098829, 28934129, ...19581421, 20203102, 26077338, 15576463, 12765939, 18597775, 17360977, 22348058, 16131083, 16099428, 25813876, 14769130, 19561084, 30381640, 11287630, 28652303, 22966072, 18952604, 17640984, 18498745, 16284649, 16354680, 21478152, 27434075, 19651622, 25799226, 21829658, 17081983, 23512499, 16123357, 36111162, 12510059
S636 Phosphorylation O75116 (ROCK2) neXtProt 16098829
S636 Phosphorylation P23443 (RPS6KB1) neXtProt   PhosphoSitePlus 18952604
S636 Phosphorylation P27361 (MAPK3) Signor 12510059
S636 Phosphorylation P28482 (MAPK1) HPRD   neXtProt   PhosphoSitePlus   Signor 19651622, 12510059, 16131083, ...17640984
S636 Phosphorylation P45983 (MAPK8) Signor 12510059
S639 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P 25667991, 25799226, 16354680, ...23512499, 19561084, 30381640, 11287630, 17640984, 20203102, 15576463, 16123357, 16099428, 21829658, 21478152, 14769130
S639 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus 17640984
Y662 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus   UniProt 15592455, 11162588, 8530377
Y662 Phosphorylation P08069 (IGF1R) PhosphoSitePlus 8530377
Y662 Phosphorylation P23458 (JAK1) HPRD 11162588
S666 Phosphorylation HPRD   PhosphoSitePlus 8626671
S668 Phosphorylation PhosphoSitePlus
S672 Phosphorylation PhosphoSitePlus
S680 Phosphorylation PhosphoSitePlus
S694 Phosphorylation PhosphoSitePlus
Y695 Phosphorylation PhosphoSitePlus
C728 Methylation IEDB 31844290
Y732 Phosphorylation HPRD   IntAct   PRO   PhosphoSitePlus 11162588, 7680095, 8530377
Y732 Phosphorylation P08069 (IGF1R) PhosphoSitePlus 8530377
Y732 Phosphorylation P23458 (JAK1) HPRD 11162588
S736 Phosphorylation HPRD 8626671
S766 Phosphorylation HPRD   PhosphoSitePlus 19664994
K772 Methylation PhosphoSitePlus
K772 Ubiquitination PhosphoSitePlus
T774 Phosphorylation PhosphoSitePlus
S794 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20135346, 31446747, 12006586, ...20363874, 20863384, 12624099, 17459875
S794 Phosphorylation Q9H0K1 (SIK2) HPRD   Signor 12624099
Y800 Phosphorylation PhosphoSitePlus
T811 Phosphorylation HPRD 8349691
T811 Phosphorylation P67870 (CSNK2B) HPRD 8349691
T847 Phosphorylation PhosphoSitePlus
T859 Phosphorylation PhosphoSitePlus
S862 Phosphorylation PhosphoSitePlus
K867 Ubiquitination PhosphoSitePlus
S892 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 16020478, 17360977
Y896 Phosphorylation HPRD   IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21939528, 17827393, 12220227, ...17902048, 8631859, 31620609, 23983791, 23401856, 11259577, 8530377, 7513703, 25886138
Y896 Phosphorylation P06213 (INSR) PhosphoSitePlus   Signor 12220227, 8530377
Y896 Phosphorylation P06241 (FYN) neXtProt 8631859
Y896 Phosphorylation P08069 (IGF1R) HPRD   PhosphoSitePlus   Signor 17827393, 8530377
T936 Phosphorylation PhosphoSitePlus
T938 Phosphorylation PhosphoSitePlus
Y941 Phosphorylation HPRD   IntAct   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22617042, 17827393, 11403293, ...12220227, 20685959, 25299696, 14632132, 26378251, 8530377
Y941 Phosphorylation P08069 (IGF1R) PhosphoSitePlus   Signor 17827393, 8530377
S974 Phosphorylation neXtProt 16098829
S974 Phosphorylation O75116 (ROCK2) neXtProt 16098829
S984 O-Glycosylation GlyGen   PhosphoSitePlus 19671924, 30397120, 35132862, ...25580119, 32798372
S984 Phosphorylation RLIMS-P 25580119
S985 O-Glycosylation GlyGen   PhosphoSitePlus 35132862, 19671924, 30397120, ...32798372
Y989 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 22709426, 17827393, 23045700, ...8530377
Y989 Phosphorylation P06213 (INSR) PhosphoSitePlus 8530377
Y989 Phosphorylation P08069 (IGF1R) PhosphoSitePlus   Signor 17827393, 8530377
S1005 Phosphorylation PhosphoSitePlus   RLIMS-P 17360977
S1011 O-Glycosylation GlyGen   PhosphoSitePlus 35132862, 19671924, 30397120, ...32798372
Y1012 Phosphorylation PhosphoSitePlus
S1025 Phosphorylation PhosphoSitePlus
S1037 Phosphorylation RLIMS-P 25580119
S1041 Phosphorylation PhosphoSitePlus
S1043 Phosphorylation PhosphoSitePlus
T1045 Phosphorylation RLIMS-P 16244361
S1057 Phosphorylation PhosphoSitePlus
S1058 Phosphorylation PhosphoSitePlus
S1070 Phosphorylation PhosphoSitePlus
S1078 Phosphorylation phospho.ELM   PhosphoSitePlus 16503154
S1084 Phosphorylation PhosphoSitePlus
S1100 Phosphorylation HPRD   PhosphoSitePlus   Signor 19651622, 17360977
S1100 Phosphorylation P17612 (PRKACA) Signor 17360977
S1101 O-Glycosylation GlyGen 35132862, 19671924, 25580119, ...30397120, 32798372
S1101 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17709744, 23352416, 22046423, ...17360977, 17081983, 18220336, 17647275, 30374127, 28934129, 18952604, 24979806, 32576196, 20203102, 25580119, 16914728, 26298773, 28674284, 15364919, 24810050, 29738527
S1101 Phosphorylation P05129 (PRKCG) HPRD 15364919
S1101 Phosphorylation P23443 (RPS6KB1) neXtProt   PhosphoSitePlus 17709744, 18952604, 16914728
S1101 Phosphorylation Q04759 (PRKCQ) HPRD   neXtProt   PhosphoSitePlus 15364919, 23352416
S1101 Phosphorylation Q05513 (PRKCZ) Signor 17360977
S1101 Phosphorylation Q05655 (PRKCD) HPRD 15364919
T1103 Phosphorylation HPRD   PhosphoSitePlus 17081983
S1105 Phosphorylation PhosphoSitePlus
T1107 Phosphorylation PhosphoSitePlus
S1109 Phosphorylation PhosphoSitePlus
T1111 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T1116 Phosphorylation PhosphoSitePlus
S1142 Phosphorylation PhosphoSitePlus
S1143 Phosphorylation HPRD   PhosphoSitePlus 17081983
S1145 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16020478, 17081983
Y1179 Phosphorylation HPRD   IntAct   neXtProt   PRO   PhosphoSitePlus   Signor 17827393, 8631859, 8530377, ...7513703, 9756938
Y1179 Phosphorylation P06213 (INSR) PhosphoSitePlus 8530377
Y1179 Phosphorylation P06241 (FYN) neXtProt 8631859
Y1179 Phosphorylation P08069 (IGF1R) PhosphoSitePlus   Signor 17827393, 8530377
K1186 Ubiquitination PhosphoSitePlus
K1189 Ubiquitination PhosphoSitePlus
S1222 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor 16020478, 17360977
S1222 Phosphorylation P17612 (PRKACA) Signor 17360977
S1223 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 16020478, 17360977, 16131083
S1223 Phosphorylation P17612 (PRKACA) Signor 17360977
Y1229 Phosphorylation HPRD   IEDB   IntAct   RLIMS-P   Signor 9756938, 7513703, 32387766, ...17827393, 12220227
Y1229 Phosphorylation P06213 (INSR) Signor 12220227
Y1229 Phosphorylation P08069 (IGF1R) Signor 17827393


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048051 (hIRS1/Phos:2) pY612,pY662,pY732,pY896,pY941,pY1179 PRO
PR:000048052 (hIRS1/PhosTyr+) p PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P35568 (IRS1) Y612 P00533 (EGFR) increased_association eFIP 17902048
Phosphorylation P35568 (IRS1) S1223 Q06124 (PTPN11) unknown eFIP 16020478
Phosphorylation P35568 (IRS1) S312 O00459 (PIK3R2) unknown eFIP 16505239
Phosphorylation P35568 (IRS1) Y612 P08069 (IGF1R) increased_association eFIP 17902048


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y46 * Biomuta DOID:1612 / breast cancer [ cosmic ]
Y46 H46 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y47 C47 Biomuta DOID:1319 / brain cancer [ cosmic ]
T88 A88 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y183 C183 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S268 I268 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S274 P274 Biomuta DOID:1319 / brain cancer [ cosmic ]
S323 A323 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S330 N330 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T335 I335 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S341 L341 Biomuta DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
R373 C373 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S383 W383 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S383 L383 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S385 L385 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S441 Y441 Biomuta DOID:1324 / lung cancer [ cosmic ]
S441 T441 Biomuta DOID:4159 / skin cancer [ cosmic ]
S441 F441 Biomuta DOID:4159 / skin cancer [ cosmic ]
S444 I444 Biomuta DOID:1324 / lung cancer [ cosmic ]
S449 P449 Biomuta DOID:1612 / breast cancer [ cosmic ]
T453 I453 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
T495 A495 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T498 I498 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T530 A530 Biomuta DOID:1324 / lung cancer [ cosmic ]
T533 I533 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
S581 Y581 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y632 C632 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S672 C672 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S672 F672 Biomuta DOID:2021 / placenta cancer [ cosmic ]
S680 C680 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y695 F695 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C728 Y728 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y732 * Biomuta DOID:1319 / brain cancer [ cosmic ]
S766 T766 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
Y800 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y800 C800 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T811 I811 Biomuta DOID:4159 / skin cancer [ cosmic ]
T811 A811 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T847 A847 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T859 M859 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:5158 / pleural cancer [ cosmic ]
T936 I936 Biomuta DOID:1319 / brain cancer [ cosmic ]
S974 I974 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S985 N985 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1005 L1005 Biomuta DOID:363 / uterine cancer [ icgc ]
S1011 I1011 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1043 F1043 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1070 I1070 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1078 I1078 Biomuta DOID:2998 / testicular cancer [ cosmic ]
S1109 C1109 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K1186 N1186 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1189 E1189 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1223 G1223 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]