iPTMnet Report for P35408 (PTGER4)
Protein Information
UniProt AC / UniProt ID | P35408 / PE2R4_HUMAN |
Protein Name | Prostaglandin E2 receptor EP4 subtype |
Gene Name | Name: PTGER4 Synonyms:PTGER2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P35408 |
PRO Name | prostaglandin E2 receptor EP4 subtype (human) |
Definition | A prostaglandin E2 receptor EP4 subtype that is encoded in the genome of human. |
Short Label | hPTGER4 |
Category | organism-gene |
P35408 (PTGER4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S222 | Phosphorylation | score2 | phospho.ELM | 11597569 | ||
S235 | Phosphorylation | score1 | PhosphoSitePlus | |||
S245 | Phosphorylation | score1 | PhosphoSitePlus | |||
S252 | Phosphorylation | score1 | PhosphoSitePlus | |||
S259 | Phosphorylation | score2 | phospho.ELM | 11597569 | ||
K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
T335 | Phosphorylation | score1 | PhosphoSitePlus | |||
S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
S354 | Phosphorylation | score2 | phospho.ELM | 11597569 | ||
S374 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus UniProt | 14709160 | ||
S377 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus UniProt | 14709160 | ||
S379 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus UniProt | 14709160 | ||
S382 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus UniProt | 14709160 | ||
S389 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 14709160 | ||
S390 | Phosphorylation | score0 | RLIMS-P | 14709160 | ||
T391 | Phosphorylation | score0 | RLIMS-P | 14709160 | ||
S392 | Phosphorylation | score0 | RLIMS-P | 14709160 | ||
T394 | Phosphorylation | score1 | PhosphoSitePlus | |||
S400 | Phosphorylation | score1 | PhosphoSitePlus | |||
S430 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11597569 | ||
T433 | Phosphorylation | score2 | phospho.ELM | 11597569 | ||
S460 | Phosphorylation | score2 | phospho.ELM | 11597569 | ||
K468 | Ubiquitination | score1 | PhosphoSitePlus | |||
S484 | Phosphorylation | score2 | phospho.ELM | 11597569 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S222 | P222 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S222 | A222 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S235 | P235 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
S354 | P354 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S354 | A354 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S392 | Y392 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T394 | I394 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S400 | L400 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S430 | P430 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S430 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
T433 | N433 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S460 | R460 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S484 | L484 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S484 | A484 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |