iPTMnet Report for P35348 (ADRA1A)
Protein Information
| UniProt AC / UniProt ID | P35348 / ADA1A_HUMAN |
| Protein Name | Alpha-1A adrenergic receptor |
| Gene Name | Name: ADRA1A Synonyms:ADRA1C; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P35348 |
| PRO Name | alpha-1A adrenergic receptor (human) |
| Definition | An alpha-1A adrenergic receptor that is encoded in the genome of human. |
| Short Label | hADRA1A |
| Category | organism-gene |
DAG ViewP35348 (ADRA1A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S227 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S229 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T233 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K239 | Acetylation | score1 | PhosphoSitePlus | |||
| K239 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K254 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S258 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T273 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S304 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C320 | Methylation | score1 | IEDB | 31844290 | ||
| S351 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S352 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S381 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T384 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S389 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S402 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S407 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T411 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S413 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T451 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T273 | Phosphorylation | score0 | HPRD | 18491316 | ||
| S304 | Phosphorylation | score0 | HPRD | 18491316 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T273 | Phosphorylation | score0 | HPRD | 18491316 | ||
| S304 | Phosphorylation | score0 | HPRD | 18491316 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T273 | Phosphorylation | score0 | HPRD | 18491316 | ||
| S304 | Phosphorylation | score0 | HPRD | 18491316 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T273 | Phosphorylation | score0 | HPRD | 18491316 | ||
| S304 | Phosphorylation | score0 | HPRD | 18491316 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K321 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T233 | K233 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T233 | M233 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S246 | R246 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| K254 | M254 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S258 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T273 | M273 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S352 | F352 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T384 | N384 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
| S402 | F402 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T411 | I411 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T451 | I451 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc ] |
