Protein Information

Cytoscape View


UniProt AC / UniProt ID P35348 / ADA1A_HUMAN
Protein Name Alpha-1A adrenergic receptor
Gene Name Name: ADRA1A
Synonyms:ADRA1C;
Organism Homo sapiens (Human)

PRO ID PR:P35348
DAG View
PRO Name alpha-1A adrenergic receptor (human)
Definition An alpha-1A adrenergic receptor that is encoded in the genome of human.
Short Label hADRA1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35348 (ADRA1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S220 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
T233 Phosphorylation PhosphoSitePlus
K239 Acetylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
T273 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
T384 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
T451 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T273 Phosphorylation HPRD 18491316
S304 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
T273 Phosphorylation HPRD 18491316
S304 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
T273 Phosphorylation HPRD 18491316
S304 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
T273 Phosphorylation HPRD 18491316
S304 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
K321 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T233 K233 Biomuta DOID:1909 / melanoma [ cosmic ]
S246 R246 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K254 M254 Biomuta DOID:1324 / lung cancer [ cosmic ]
T273 M273 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, tcga ]
T451 I451 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]