iPTMnet Report for P34932 (HSPA4)
Protein Information
UniProt AC / UniProt ID | P34932 / HSP74_HUMAN |
Protein Name | Heat shock 70 kDa protein 4 |
Gene Name | Name: HSPA4 Synonyms:APG2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P34932 |
PRO Name | heat shock 70 kDa protein 4 (human) |
Definition | A heat shock 70 kDa protein 4 that is encoded in the genome of human. |
Short Label | hHSPA4 |
Category | organism-gene |
P34932 (HSPA4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S12 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y30 | Phosphorylation | score1 | PhosphoSitePlus | |||
S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
R33 | Methylation | score1 | PhosphoSitePlus | |||
C34 | S-Nitrosylation | score0 | dbSNO | 19483679, 26338901 | ||
C38 | S-Nitrosylation | score0 | dbSNO | 19483679, 26338901 | ||
K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
K53 | Acetylation | score1 | PhosphoSitePlus | |||
K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
S58 | Phosphorylation | score1 | PhosphoSitePlus | |||
K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
S76 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 21406692, ... | ||
K84 | Ubiquitination | score1 | PhosphoSitePlus | |||
S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y89 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15592455 | ||
T96 | Phosphorylation | score1 | PhosphoSitePlus | |||
T99 | Phosphorylation | score1 | PhosphoSitePlus | |||
K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
T113 | Phosphorylation | score1 | PhosphoSitePlus | |||
T114 | Phosphorylation | score1 | PhosphoSitePlus | |||
T118 | Phosphorylation | score1 | PhosphoSitePlus | |||
S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
S155 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y184 | Phosphorylation | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
K194 | Acetylation | score1 | PhosphoSitePlus | |||
K194 | Ubiquitination | score1 | PhosphoSitePlus | |||
K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
T229 | Phosphorylation | score0 | RLIMS-P | 20072699 | ||
T230 | Phosphorylation | score1 | PhosphoSitePlus | |||
K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
C245 | S-Nitrosylation | score0 | dbSNO | 20140087 | ||
K250 | Ubiquitination | score1 | PhosphoSitePlus | |||
R265 | Methylation | score1 | PhosphoSitePlus | |||
C270 | Methylation | score1 | IEDB | 31844290 | ||
K272 | Acetylation | score1 | PhosphoSitePlus | |||
K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
S287 | Phosphorylation | score1 | PhosphoSitePlus | |||
K305 | Ubiquitination | score1 | PhosphoSitePlus | |||
K329 | Acetylation | score1 | PhosphoSitePlus | |||
K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
K332 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y336 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15592455, 19690332 | ||
K351 | Ubiquitination | score1 | PhosphoSitePlus | |||
K356 | Acetylation | score1 | PhosphoSitePlus | |||
K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
S384 | Phosphorylation | score1 | PhosphoSitePlus | |||
K388 | Methylation | score1 | PhosphoSitePlus | |||
K388 | Ubiquitination | score1 | PhosphoSitePlus | |||
S393 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S408 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 25900241 | ||
S415 | Phosphorylation | score1 | PhosphoSitePlus | |||
C417 | S-Nitrosylation | score0 | dbSNO | 19483679, 26338901 | ||
K422 | Acetylation | score1 | PhosphoSitePlus | |||
K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
S429 | Phosphorylation | score1 | PhosphoSitePlus | |||
K430 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K430 | Ubiquitination | score1 | PhosphoSitePlus | |||
T433 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y435 | Phosphorylation | score1 | PhosphoSitePlus | |||
K437 | Ubiquitination | score1 | PhosphoSitePlus | |||
K466 | Ubiquitination | score1 | PhosphoSitePlus | |||
S475 | Phosphorylation | score1 | PhosphoSitePlus | |||
S476 | Phosphorylation | score1 | PhosphoSitePlus | |||
K477 | Ubiquitination | score1 | PhosphoSitePlus | |||
K517 | Ubiquitination | score1 | PhosphoSitePlus | |||
T538 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
K543 | Ubiquitination | score1 | PhosphoSitePlus | |||
S546 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S552 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
S556 | Phosphorylation | score1 | PhosphoSitePlus | |||
K557 | Methylation | score1 | PhosphoSitePlus | |||
K557 | Ubiquitination | score1 | PhosphoSitePlus | |||
K559 | Methylation | score1 | PhosphoSitePlus | |||
K560 | Acetylation | score1 | PhosphoSitePlus | |||
K568 | Ubiquitination | score1 | PhosphoSitePlus | |||
K573 | Ubiquitination | score1 | PhosphoSitePlus | |||
T576 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
K603 | Acetylation | score1 | PhosphoSitePlus | |||
K609 | Ubiquitination | score1 | PhosphoSitePlus | |||
K618 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y624 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y626 | Phosphorylation | score1 | PhosphoSitePlus | |||
K631 | Acetylation | score1 | PhosphoSitePlus | |||
K631 | Ubiquitination | score1 | PhosphoSitePlus | |||
S633 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y636 | Phosphorylation | score1 | PhosphoSitePlus | |||
K638 | Ubiquitination | score1 | PhosphoSitePlus | |||
S641 | Phosphorylation | score1 | PhosphoSitePlus | |||
R645 | Methylation | score1 | PhosphoSitePlus | |||
S647 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y660 | Phosphorylation | score1 | PhosphoSitePlus | |||
K668 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y671 | Phosphorylation | score1 | PhosphoSitePlus | |||
K674 | Acetylation | score1 | PhosphoSitePlus | |||
K674 | Ubiquitination | score1 | PhosphoSitePlus | |||
K679 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K679 | Ubiquitination | score1 | PhosphoSitePlus | |||
K686 | Ubiquitination | score1 | PhosphoSitePlus | |||
S692 | Phosphorylation | score1 | PhosphoSitePlus | |||
K697 | Ubiquitination | score1 | PhosphoSitePlus | |||
K704 | Ubiquitination | score1 | PhosphoSitePlus | |||
K711 | Ubiquitination | score1 | PhosphoSitePlus | |||
K717 | Ubiquitination | score1 | PhosphoSitePlus | |||
K719 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y723 | Phosphorylation | score1 | PhosphoSitePlus | |||
K733 | Ubiquitination | score1 | PhosphoSitePlus | |||
K736 | Ubiquitination | score1 | PhosphoSitePlus | |||
S737 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
T738 | O-Glycosylation | score1 | GlyGen | 16408927, 33214551, 35138101, ... | ||
K748 | Ubiquitination | score1 | PhosphoSitePlus | |||
K754 | Ubiquitination | score1 | PhosphoSitePlus | |||
S756 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K773 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
K773 | Ubiquitination | score1 | PhosphoSitePlus | |||
C779 | Methylation | score1 | IEDB | 31844290 | ||
S780 | Phosphorylation | score1 | PhosphoSitePlus | |||
S784 | Phosphorylation | score1 | PhosphoSitePlus | |||
K785 | Ubiquitination | score1 | PhosphoSitePlus | |||
K789 | Ubiquitination | score1 | PhosphoSitePlus | |||
K794 | Ubiquitination | score1 | PhosphoSitePlus | |||
K798 | Ubiquitination | score1 | PhosphoSitePlus | |||
S828 | Phosphorylation | score1 | PhosphoSitePlus | |||
S830 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S54 | Phosphorylation | score0 | HPRD | 18767875 | ||
S58 | Phosphorylation | score0 | HPRD | 18767875 | ||
S76 | Phosphorylation | score0 | HPRD | 19664994, 18669648, 20058876 | ||
T113 | Phosphorylation | score0 | HPRD | 19664995 | ||
T114 | Phosphorylation | score0 | HPRD | 19664995 | ||
T118 | Phosphorylation | score0 | HPRD | 19664995 | ||
Y336 | Phosphorylation | score0 | HPRD | 15592455 | ||
S384 | Phosphorylation | score0 | HPRD | 20068231 | ||
T395 | Phosphorylation | score0 | HPRD | 20068231 | ||
S415 | Phosphorylation | score0 | HPRD | 19413330 | ||
S429 | Phosphorylation | score0 | HPRD | 20068231 | ||
S474 | Phosphorylation | score0 | HPRD | 20068231 | ||
T538 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S546 | Phosphorylation | score0 | HPRD | 19664994 | ||
S552 | Phosphorylation | score0 | HPRD | 17525332 | ||
T576 | Phosphorylation | score0 | HPRD | 18669648 | ||
T776 | Phosphorylation | score0 | HPRD | 20068231 | ||
S777 | Phosphorylation | score0 | HPRD | 20068231 | ||
S780 | Phosphorylation | score0 | HPRD | 20068231 | ||
S784 | Phosphorylation | score0 | HPRD | 20068231 |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | Q92574 (TSC1) | T417 | P34932 (HSPA4) | unknown | eFIP | 20006582 |