iPTMnet Report for P30838 (ALDH3A1)
Protein Information
UniProt AC / UniProt ID | P30838 / AL3A1_HUMAN |
Protein Name | Aldehyde dehydrogenase, dimeric NADP-preferring |
Gene Name | Name: ALDH3A1 Synonyms:ALDH3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P30838 |
PRO Name | aldehyde dehydrogenase, dimeric NADP-preferring (human) |
Definition | An aldehyde dehydrogenase, dimeric NADP-preferring that is encoded in the genome of human. |
Short Label | hALDH3A1 |
Category | organism-gene |
P30838 (ALDH3A1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 22814378 | ||
K3 | Acetylation | score1 | PhosphoSitePlus | |||
S5 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
Y163 | Phosphorylation | score1 | PhosphoSitePlus | |||
K178 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
K194 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
T198 | Phosphorylation | score1 | PhosphoSitePlus | |||
K202 | Acetylation | score1 | PhosphoSitePlus | |||
T205 | Phosphorylation | score1 | PhosphoSitePlus | |||
K214 | Ubiquitination | score1 | PhosphoSitePlus | |||
K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
K269 | Acetylation | score1 | PhosphoSitePlus | |||
K269 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y272 | Phosphorylation | score1 | PhosphoSitePlus | |||
K277 | Acetylation | score1 | PhosphoSitePlus | |||
K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
K302 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y305 | Phosphorylation | score1 | PhosphoSitePlus | |||
S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y443 | Phosphorylation | score1 | PhosphoSitePlus | |||
S446 | Phosphorylation | score1 | PhosphoSitePlus | |||
T451 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S5 | G5 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T198 | M198 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
K202 | E202 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K202 | N202 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T205 | S205 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
K221 | N221 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
Y272 | C272 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K302 | E302 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S446 | I446 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T451 | I451 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |