iPTMnet Report for P30556 (AGTR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P30556 / AGTR1_HUMAN
Protein Name Type-1 angiotensin II receptor
Gene Name Name: AGTR1
Synonyms:AGTR1A,AGTR1B,AT2R1,AT2R1B;
Organism Homo sapiens (Human)

PRO ID PR:P30556
DAG View
PRO Name type-1 angiotensin II receptor (human)
Definition An angiotensin II receptor 1 that is encoded in the genome of human.
Short Label hAGTR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P30556 (AGTR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N4 N-Glycosylation GlyGen   UniProt 19139490
Y26 Phosphorylation PhosphoSitePlus
N176 N-Glycosylation GlyGen   UniProt 32079768, 30639100
K230 Ubiquitination PhosphoSitePlus
C289 S-Nitrosylation dbSNO 22178444, 16565729
Y302 Phosphorylation HPRD 12436935
Y319 Phosphorylation HPRD   IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P 12522132, 9516477
Y319 Phosphorylation P12931 (SRC) PhosphoSitePlus 9516477
T332 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N176 S176 Biomuta DOID:1324 / lung cancer [ cosmic ]
C289 R289 Biomuta DOID:4159 / skin cancer [ cosmic ]
S335 N335 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T336 M336 Biomuta [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ] DOID:11934 / head and neck cancer [ icgc ]
S338 F338 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]