iPTMnet Report for P30556 (AGTR1)
Protein Information
| UniProt AC / UniProt ID | P30556 / AGTR1_HUMAN |
| Protein Name | Type-1 angiotensin II receptor |
| Gene Name | Name: AGTR1 Synonyms:AGTR1A,AGTR1B,AT2R1,AT2R1B; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P30556 |
| PRO Name | type-1 angiotensin II receptor (human) |
| Definition | An angiotensin II receptor 1 that is encoded in the genome of human. |
| Short Label | hAGTR1 |
| Category | organism-gene |
DAG ViewP30556 (AGTR1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N4 | N-Glycosylation | score2 | GlyGen UniProt | 19139490 | ||
| Y26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N176 | N-Glycosylation | score4 | GlyGen UniProt | 32079768, 30639100 | ||
| K230 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C289 | S-Nitrosylation | score2 | dbSNO | 22178444, 16565729 | ||
| Y302 | Phosphorylation | score1 | HPRD | 12436935 | ||
| Y319 | Phosphorylation | P12931 (SRC) | score4 | HPRD IntAct phospho.ELM PhosphoSitePlus RLIMS-P | 12522132, 9516477 | |
| T332 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S335 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T336 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S342 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N176 | S176 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| C289 | R289 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S335 | N335 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T336 | M336 | Biomuta | [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ] DOID:11934 / head and neck cancer [ icgc ] | |
| S338 | F338 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] |
