iPTMnet Report for P24863 (CCNC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P24863 / CCNC_HUMAN
Protein Name Cyclin-C
Gene Name Name: CCNC
Organism Homo sapiens (Human)

PRO ID PR:P24863
DAG View
PRO Name cyclin-C (human)
Definition A cyclin-C that is encoded in the genome of human.
Short Label hCCNC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P24863 (CCNC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K30 Ubiquitination PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
Y122 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
C189 Methylation IEDB 31844290
K248 Ubiquitination PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus   UniProt 17525332
S278 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
Y280 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S121 Phosphorylation HPRD 17924679
Y122 Phosphorylation HPRD 17924679
T252 Phosphorylation HPRD 20068231
S275 Phosphorylation HPRD 18691976, 17525332, 18077418
S278 Phosphorylation HPRD 18077418
S279 Phosphorylation HPRD 17525332
S281 Phosphorylation HPRD 17525332, 18077418
Site PTM Type PTM Enzyme Score Source PMID
S36 Phosphorylation HPRD 17924679
Y37 Phosphorylation HPRD 17924679
T167 Phosphorylation HPRD 20068231
S190 Phosphorylation HPRD 18691976, 17525332, 18077418
S193 Phosphorylation HPRD 18077418
S194 Phosphorylation HPRD 17525332
S196 Phosphorylation HPRD 17525332, 18077418


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S33 L33 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S33 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K248 T248 Biomuta DOID:363 / uterine cancer [ cosmic ]