iPTMnet Report for P24530 (EDNRB)
Protein Information
UniProt AC / UniProt ID | P24530 / EDNRB_HUMAN |
Protein Name | Endothelin receptor type B precursor |
Gene Name | Name: EDNRB Synonyms:ETRB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P24530 |
PRO Name | endothelin receptor type B (human) |
Definition | An endothelin receptor type B that is encoded in the genome of human. |
Short Label | hEDNRB |
Category | organism-gene |
P24530 (EDNRB) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C8 | Methylation | score1 | IEDB | 31844290 | ||
T52 | Phosphorylation | score1 | PhosphoSitePlus | |||
S80 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y200 | Phosphorylation | score1 | PhosphoSitePlus | |||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
S305 | Phosphorylation | score1 | PhosphoSitePlus | |||
S407 | Phosphorylation | score1 | PhosphoSitePlus | |||
S419 | Phosphorylation | score1 | PhosphoSitePlus | |||
C420 | Methylation | score1 | IEDB | 31844290 | ||
Y430 | Phosphorylation | score1 | PhosphoSitePlus | |||
S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
S436 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y439 | Phosphorylation | score1 | PhosphoSitePlus | |||
S440 | Phosphorylation | score1 | PhosphoSitePlus | |||
S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
S442 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y200 | Phosphorylation | score1 | HPRD | 14636059 | ||
S205 | Phosphorylation | score1 | HPRD | 14636059 | ||
S305 | Phosphorylation | score1 | HPRD | 14636059 | ||
S407 | Phosphorylation | score1 | HPRD | 14636059 | ||
S413 | Phosphorylation | score1 | HPRD | 14636059 | ||
S419 | Phosphorylation | score1 | HPRD | 14636059 | ||
Y430 | Phosphorylation | score2 | HPRD | 19901323, 14636059 | ||
S435 | Phosphorylation | score1 | HPRD | 14636059 | ||
S436 | Phosphorylation | score1 | HPRD | 14636059 | ||
Y439 | Phosphorylation | score1 | HPRD | 14636059 | ||
S440 | Phosphorylation | score1 | HPRD | 14636059 | ||
S441 | Phosphorylation | score1 | HPRD | 14636059 | ||
S442 | Phosphorylation | score1 | HPRD | 14636059 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T52 | A52 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S80 | P80 | Biomuta | DOID:10534 / stomach cancer [ cosmic, cosmic ] DOID:5041 / esophageal cancer [ cosmic ] | |
S205 | F205 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S305 | R305 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S419 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
C420 | Y420 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S436 | C436 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S440 | R440 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] |