iPTMnet Report for P24530 (EDNRB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P24530 / EDNRB_HUMAN
Protein Name Endothelin receptor type B precursor
Gene Name Name: EDNRB
Synonyms:ETRB;
Organism Homo sapiens (Human)

PRO ID PR:P24530
DAG View
PRO Name endothelin receptor type B (human)
Definition An endothelin receptor type B that is encoded in the genome of human.
Short Label hEDNRB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P24530 (EDNRB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C8 Methylation IEDB 31844290
T52 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
C420 Methylation IEDB 31844290
Y430 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
Y439 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y200 Phosphorylation HPRD 14636059
S205 Phosphorylation HPRD 14636059
S305 Phosphorylation HPRD 14636059
S407 Phosphorylation HPRD 14636059
S413 Phosphorylation HPRD 14636059
S419 Phosphorylation HPRD 14636059
Y430 Phosphorylation HPRD 19901323, 14636059
S435 Phosphorylation HPRD 14636059
S436 Phosphorylation HPRD 14636059
Y439 Phosphorylation HPRD 14636059
S440 Phosphorylation HPRD 14636059
S441 Phosphorylation HPRD 14636059
S442 Phosphorylation HPRD 14636059
Site PTM Type PTM Enzyme Score Source PMID
Y200 Phosphorylation HPRD 14636059
S205 Phosphorylation HPRD 14636059
S305 Phosphorylation HPRD 14636059


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T52 A52 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S80 P80 Biomuta DOID:10534 / stomach cancer [ cosmic, cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S205 F205 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S305 R305 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S419 * Biomuta DOID:4159 / skin cancer [ cosmic ]
C420 Y420 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S436 C436 Biomuta DOID:1324 / lung cancer [ cosmic ]
S440 R440 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]