iPTMnet Report for P24462 (CYP3A7)
Protein Information
| UniProt AC / UniProt ID | P24462 / CP3A7_HUMAN |
| Protein Name | Cytochrome P450 3A7 |
| Gene Name | Name: CYP3A7 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P24462 |
| PRO Name | cytochrome P450 3A7 (human) |
| Definition | A cytochrome P450 3A7 that is encoded in the genome of human. |
| Short Label | hCYP3A7 |
| Category | organism-gene |
DAG ViewP24462 (CYP3A7) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R158 | Methylation | score1 | PhosphoSitePlus | |||
| R161 | Methylation | score1 | PhosphoSitePlus | |||
| S284 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T286 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K406 | Methylation | score1 | PhosphoSitePlus | |||
| Y432 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T485 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R158 | K158 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| R158 | I158 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| R161 | K161 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| T286 | S286 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T286 | I286 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| Y432 | C432 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] |
