iPTMnet Report for P23769 (GATA2)
Protein Information
UniProt AC / UniProt ID | P23769 / GATA2_HUMAN |
Protein Name | Endothelial transcription factor GATA-2 |
Gene Name | Name: GATA2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P23769 |
PRO Name | endothelial transcription factor GATA-2 (human) |
Definition | An endothelial transcription factor GATA-2 that is encoded in the genome of human. |
Short Label | hGATA2 |
Category | organism-gene |
P23769 (GATA2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S71 | Phosphorylation | score1 | PhosphoSitePlus | |||
S73 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
R86 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
T176 | Phosphorylation | P06493 (CDK1) | score2 | PhosphoSitePlus | 25670854 | |
S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
S186 | Phosphorylation | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 23186163, 25056917 | ||
Y213 | Phosphorylation | score1 | PhosphoSitePlus | |||
S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
S276 | Phosphorylation | score1 | PhosphoSitePlus | |||
S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y314 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y322 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y376 | Phosphorylation | score1 | PhosphoSitePlus | |||
K389 | Sumoylation | score1 | PhosphoSitePlus | |||
S401 | Phosphorylation | P31749 (AKT1) | score3 | neXtProt PhosphoSitePlus Signor | 15837948 | |
K409 | Ubiquitination | score1 | PhosphoSitePlus |
Proteoform PPIs
Protein 1 | Relation | Protein 2 | Source | PMID | |
---|---|---|---|---|---|
PR:P29590-4 (hPML/iso:4) | Interaction | PR:P23769 (hGATA2) | PRO | 10938104 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S73 | R73 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
S119 | R119 | Biomuta | DOID:9256 / colorectal cancer [ icgc, tcga ] | |
Y213 | F213 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc, tcga ] |