iPTMnet Report P22216 RAD53

Protein Information

UniProt AC / UniProt ID	P22216 / RAD53_YEAST
Protein Name	Serine/threonine-protein kinase RAD53
Gene Name	Name: RAD53 Synonyms:MEC2,SAD1,SPK1;OrderedLocusNames:YPL153C;ORFNames:P2588;
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID	PR:P22216 DAG View
PRO Name	serine/threonine-protein kinase RAD53 (yeast)
Definition	A protein that is a translation product of the RAD53 gene in yeast.
Short Label	yRAD53
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P22216 (RAD53) as Substrate

P22216

Condensed View

Search:

Site Select all By amino acid All Serine All Threonine By position T5 T8 S11 T12 T15 S24 S49 S53 S82 S165 T170 S171 S175 T179 S180 S181 T182 S184 S185 S198 S350 T354 T358 S373 S375 S411 S424 S473 S475 S480 S485 S489 T543 S547 T552 S560 T563 S568 S569 S586 S591 S635 S639 T731 S743 S745 S746 S747 S748 S750 S757 T759 S766 S774 S789 S791 S793 S795 T811 S812 S821	PTM Type Select all Phosphorylation	PTM Enzyme Select all P00546 (CDC28) P24869 (CLB2) P38110 (TEL1) P38111 (MEC1)	Score Select all 0 1 2 3 4	Source Select all BioGRID RLIMS-P SGD UniProt	PMID
T5	Phosphorylation		score2	SGD	24302356, 33481703
T8	Phosphorylation		score2	SGD	24302356, 33481703
S11	Phosphorylation		score2	SGD	24302356, 33491328
T12	Phosphorylation		score1	SGD	24302356
T15	Phosphorylation		score1	SGD	24302356
S24	Phosphorylation		score4	BioGRID SGD UniProt	15972895, 24302356, 33491328, ...18407956
S49	Phosphorylation		score2	BioGRID	15972895
S53	Phosphorylation		score2	SGD	24302356, 33491328
S82	Phosphorylation		score1	SGD	24302356
S165	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 17287358
T170	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 20489023
S171	Phosphorylation		score4	BioGRID SGD	16085488, 20489023
S175	Phosphorylation		score4	BioGRID SGD UniProt	24302356, 33481703, 32597660, ...18407956, 33491328, 21126336, 23749301, 15972895
T179	Phosphorylation		score1	SGD	24302356
S180	Phosphorylation		score1	SGD	24302356
S181	Phosphorylation		score4	BioGRID SGD	24302356, 18407956
T182	Phosphorylation		score2	SGD	24302356, 18407956
S184	Phosphorylation		score4	BioGRID SGD	16085488, 24302356
S185	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 18407956
S198	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 33491328
S350	Phosphorylation		score4	BioGRID RLIMS-P SGD	16085488, 24302356, 33491328, ...15972895, 18407956
T354	Phosphorylation		score4	BioGRID RLIMS-P SGD	24302356, 20489023, 18407956, ...16085488, 33491328, 17114794
T358	Phosphorylation		score1	SGD	24302356
S373	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 33481703, ...15972895, 33491328
S375	Phosphorylation		score4	BioGRID SGD	24302356, 33481703, 20489023, ...18407956, 16085488, 33491328, 15972895
S411	Phosphorylation		score4	BioGRID SGD	16085488, 33491328
S424	Phosphorylation		score4	BioGRID SGD	15972895, 24302356, 33491328, ...17563356, 17287358
S473	Phosphorylation		score2	SGD	24302356, 33491328
S475	Phosphorylation		score0	SGD	33491328
S480	Phosphorylation		score2	SGD	24302356, 33491328
S485	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 20190278, ...33491328
S485	Phosphorylation	P38110 (TEL1)	score3	BioGRID	16085488, 20190278
S485	Phosphorylation	P38111 (MEC1)	score3	BioGRID	16085488, 20190278
S489	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 20190278, ...15972895, 33491328
S489	Phosphorylation	P38110 (TEL1)	score3	BioGRID	16085488, 20190278, 15972895
S489	Phosphorylation	P38111 (MEC1)	score3	BioGRID	16085488, 20190278, 15972895
T543	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 33491328, ...15972895
S547	Phosphorylation		score4	BioGRID SGD UniProt	24302356, 18407956, 33491328, ...16085488, 23749301, 15972895
T552	Phosphorylation		score1	SGD	24302356
S560	Phosphorylation		score4	BioGRID SGD UniProt	24302356, 17563356, 20489023, ...18407956, 23749301, 16085488, 33491328, 15972895
T563	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 33491328, ...18407956
S568	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 33491328
S569	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 33491328
S586	Phosphorylation		score1	SGD	24302356
S591	Phosphorylation		score0	SGD	33491328
S635	Phosphorylation		score4	BioGRID SGD	24302356, 20489023
S639	Phosphorylation		score1	SGD	24302356
T731	Phosphorylation		score4	BioGRID SGD	19779198, 24302356
S743	Phosphorylation		score1	SGD	24302356
S745	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 23749301
S746	Phosphorylation		score4	BioGRID SGD	16085488, 24302356
S747	Phosphorylation		score4	BioGRID SGD	19779198, 24302356
S748	Phosphorylation		score4	BioGRID SGD	24302356, 20489023, 18407956, ...16085488, 23749301, 15972895
S750	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 33481703, ...33491328, 23749301
S757	Phosphorylation		score1	SGD	24302356
T759	Phosphorylation		score1	SGD	24302356
S766	Phosphorylation		score2	SGD	24302356, 23749301, 33491328
S774	Phosphorylation		score4	BioGRID RLIMS-P SGD UniProt	24302356, 17563356, 20046099, ...20489023, 18407956, 23749301, 19779198, 19801655, 33491328, 15972895
S774	Phosphorylation	P00546 (CDC28)	score3	BioGRID	19801655, 15972895, 20489023, ...17563356, 18407956
S774	Phosphorylation	P24869 (CLB2)	score3	BioGRID	19801655, 15972895, 20489023, ...17563356, 18407956
S789	Phosphorylation		score4	BioGRID RLIMS-P SGD	24302356, 33481703, 17563356, ...20046099, 20489023, 18407956, 23749301, 16085488, 33491328, 15972895
S791	Phosphorylation		score4	BioGRID RLIMS-P SGD	24302356, 17563356, 20046099, ...18407956, 16085488, 33491328
S793	Phosphorylation		score4	BioGRID SGD UniProt	24302356, 33481703, 17563356, ...20489023, 18407956, 33491328, 16085488, 23749301, 15972895
S795	Phosphorylation		score4	BioGRID SGD	16085488, 24302356, 33481703, ...18407956
T811	Phosphorylation		score1	SGD	22323608
S812	Phosphorylation		score2	SGD	24302356, 22323608, 33491328, ...18407956
S821	Phosphorylation		score1	SGD	22323608

P22216 (RAD53) as PTM Enzyme

Protein as Phosphorylation Enzyme

Search:

	Substrate Select all P39705 (NUP60)	Site Select all By amino acid All Serine By position S382	Score Select all 1	Source Select all BioGRID	PMID
	P39705 (NUP60)	S382	score1	BioGRID	17563356, 15665377, 20702584, ...18407956, 17287358, 19779198, 21177495

PTM-dependent PPI

Search:

	PTM type Select all Phosphorylation	Substrate Select all P46946 (SAE2)	Site Select all By amino acid All Threonine By position T90	Interactant Select all P22216 (RAD53)	Association type Select all unknown	Source Select all eFIP	PMID
	Phosphorylation	P46946 (SAE2)	T90	P22216 (RAD53)	unknown	eFIP	25762720

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for P22216 (RAD53)

Protein Information

Interactive Sequence View

P22216 (RAD53) as Substrate

P22216 (RAD53) as PTM Enzyme

PTM-dependent PPI