Protein Information

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UniProt AC / UniProt ID P22216 / RAD53_YEAST
Protein Name Serine/threonine-protein kinase RAD53
Gene Name Name: RAD53
Synonyms:MEC2,SAD1,SPK1;OrderedLocusNames:YPL153C;ORFNames:P2588;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P22216
DAG View
PRO Name serine/threonine-protein kinase RAD53 (yeast)
Definition A protein that is a translation product of the RAD53 gene in yeast.
Short Label yRAD53
Category organism-gene

Interactive Sequence View

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P22216 (RAD53) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoGrid   UniProt 15972895, 18407956
S49 Phosphorylation PhosphoGrid 15972895
S165 Phosphorylation PhosphoGrid 16085488, 17287358
T170 Phosphorylation PhosphoGrid 16085488, 20489023
S171 Phosphorylation PhosphoGrid 16085488, 20489023
S175 Phosphorylation PhosphoGrid   UniProt 21126336, 15972895, 18407956
S181 Phosphorylation PhosphoGrid 18407956
S184 Phosphorylation PhosphoGrid 16085488
S185 Phosphorylation PhosphoGrid 16085488, 18407956
S198 Phosphorylation PhosphoGrid 16085488
S350 Phosphorylation PhosphoGrid   RLIMS-P 16085488, 24302356, 15972895
T354 Phosphorylation PhosphoGrid   RLIMS-P 16085488, 24302356, 20489023, ...17114794
S373 Phosphorylation PhosphoGrid 16085488, 15972895
S375 Phosphorylation PhosphoGrid 16085488, 20489023, 15972895, ...18407956
S411 Phosphorylation PhosphoGrid 16085488
S424 Phosphorylation PhosphoGrid 15972895, 17563356, 17287358
S485 Phosphorylation P38110 (TEL1) , P38111 (MEC1) PhosphoGrid 16085488, 20190278
S489 Phosphorylation P38111 (MEC1) , P38110 (TEL1) PhosphoGrid 16085488, 20190278, 15972895
T543 Phosphorylation PhosphoGrid 16085488, 15972895
S547 Phosphorylation PhosphoGrid   UniProt 16085488, 15972895, 18407956
S560 Phosphorylation PhosphoGrid   UniProt 16085488, 15972895, 20489023, ...17563356, 18407956
T563 Phosphorylation PhosphoGrid 16085488, 18407956
S568 Phosphorylation PhosphoGrid 16085488
S569 Phosphorylation PhosphoGrid 16085488
S635 Phosphorylation PhosphoGrid 20489023
T731 Phosphorylation PhosphoGrid 19779198
S745 Phosphorylation PhosphoGrid 16085488
S746 Phosphorylation PhosphoGrid 16085488
S747 Phosphorylation PhosphoGrid 19779198
S748 Phosphorylation PhosphoGrid 16085488, 20489023, 15972895, ...18407956
S750 Phosphorylation PhosphoGrid 16085488
S774 Phosphorylation P24869 (CLB2) , P00546 (CDC28) PhosphoGrid   RLIMS-P   UniProt 17563356, 20046099, 20489023, ...18407956, 19779198, 19801655, 15972895
S789 Phosphorylation PhosphoGrid   RLIMS-P 17563356, 20046099, 20489023, ...18407956, 16085488, 15972895
S791 Phosphorylation PhosphoGrid   RLIMS-P 20046099, 16085488, 17563356, ...18407956
S793 Phosphorylation PhosphoGrid   UniProt 16085488, 15972895, 20489023, ...17563356, 18407956
S795 Phosphorylation PhosphoGrid 16085488, 18407956


P22216 (RAD53) as PTM Enzyme



Substrate Site Score Source PMID
P39705 (NUP60) S382 PhosphoGrid 17563356, 15665377, 20702584, ...18407956, 17287358, 19779198, 21177495


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P46946 (SAE2) T90 P22216 (RAD53) unknown eFIP 25762720