iPTMnet Report for P21589 (NT5E)
Protein Information
| UniProt AC / UniProt ID | P21589 / 5NTD_HUMAN |
| Protein Name | 5'-nucleotidase precursor |
| Gene Name | Name: NT5E Synonyms:NT5,NTE; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P21589 |
| PRO Name | 5'-nucleotidase (human) |
| Definition | A 5'-nucleotidase that is encoded in the genome of human. |
| Short Label | hNT5E |
| Category | organism-gene |
DAG ViewP21589 (NT5E) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K133 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S155 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N311 | N-Glycosylation | score4 | GlyGen UniProt | 23090970, 23142347, 22997138, ... | ||
| S319 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K321 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N333 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 24190977, 19159218, ... | ||
| N403 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
| S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C554 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N311 | K311 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K321 | N321 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
| N333 | T333 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| N403 | S403 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| C554 | Y554 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
