Protein Information

Cytoscape View

UniProt AC / UniProt ID P21589 / 5NTD_HUMAN
Protein Name 5'-nucleotidase precursor
Gene Name Name: NT5E
Organism Homo sapiens (Human)

PRO ID PR:P21589
DAG View
PRO Name 5'-nucleotidase (human)
Definition A 5'-nucleotidase that is encoded in the genome of human.
Short Label hNT5E
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P21589 (NT5E) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K133 Ubiquitination PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
N311 N-Glycosylation GlyGen   UniProt 23142347, 23090970, 19159218, ...24190977
S319 Phosphorylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
N333 N-Glycosylation GlyGen   UniProt 23090970, 19349973, 19159218, ...24190977
N403 N-Glycosylation GlyGen   UniProt 19159218
S520 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K262 N262 Biomuta DOID:3571 / liver cancer [ icgc ]
S319 I319 Biomuta DOID:363 / uterine cancer [ tcga ]
K321 N321 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
N333 T333 Biomuta DOID:363 / uterine cancer [ tcga ]