Protein Information

Cytoscape View


UniProt AC / UniProt ID P21589 / 5NTD_HUMAN
Protein Name 5'-nucleotidase precursor
Gene Name Name: NT5E
Synonyms:NT5,NTE;
Organism Homo sapiens (Human)

PRO ID PR:P21589
DAG View
PRO Name 5'-nucleotidase (human)
Definition A 5'-nucleotidase that is encoded in the genome of human.
Short Label hNT5E
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21589 (NT5E) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K133 Ubiquitination PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
N311 N-Glycosylation UniProt 23142347, 19159218
S319 Phosphorylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
N333 N-Glycosylation UniProt 19159218, 19349973
N403 N-Glycosylation UniProt 19159218
S520 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K262 N262 Biomuta DOID:3571 / liver cancer [ icgc ]
S319 I319 Biomuta DOID:363 / uterine cancer [ tcga ]
K321 N321 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
N333 T333 Biomuta DOID:363 / uterine cancer [ tcga ]