iPTMnet Report for P21462 (FPR1)
Protein Information
| UniProt AC / UniProt ID | P21462 / FPR1_HUMAN |
| Protein Name | fMet-Leu-Phe receptor |
| Gene Name | Name: FPR1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P21462 |
| PRO Name | fMet-Leu-Phe receptor (human) |
| Definition | An fMet-Leu-Phe receptor that is encoded in the genome of human. |
| Short Label | hFPR1 |
| Category | organism-gene |
DAG ViewP21462 (FPR1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N4 | N-Glycosylation | score2 | GlyGen | 12565836 | ||
| N10 | N-Glycosylation | score2 | GlyGen | 12565836 | ||
| Y22 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T325 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S328 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 7836371 | ||
| S328 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) | score1 | HPRD | 7836371 | |
| T329 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 7836371 | ||
| T329 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) | score1 | HPRD | 7836371 | |
| T331 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 7836371 | ||
| T331 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) | score1 | HPRD | 7836371 | |
| S332 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 7836371 | ||
| S332 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) | score1 | HPRD | 7836371 | |
| T334 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 7836371 | ||
| T334 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) | score1 | HPRD | 7836371 | |
| T336 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 7836371 | ||
| T336 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) | score1 | HPRD | 7836371 | |
| S338 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 7836371 | ||
| S338 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) | score1 | HPRD | 7836371 | |
| T339 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 7836371 | ||
| T339 | Phosphorylation | A0A0S2Z3I6 (ADRBK1) | score1 | HPRD | 7836371 | |
| S342 | Phosphorylation | score3 | neXtProt PhosphoSitePlus RLIMS-P | 22447027 | ||
| S342 | Phosphorylation | Q16539 (MAPK14) | score3 | neXtProt PhosphoSitePlus | 22447027 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | P21462 (FPR1) | S342 | P25098 (GRK2) | inhibited_association | eFIP | 22447027 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N4 | H4 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S211 | R211 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S215 | F215 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S215 | P215 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S220 | N220 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S328 | A328 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| T336 | I336 | Biomuta | [ cosmic ] | |
| S342 | Y342 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
