Protein Information

Cytoscape View


UniProt AC / UniProt ID P21462 / FPR1_HUMAN
Protein Name fMet-Leu-Phe receptor
Gene Name Name: FPR1
Organism Homo sapiens (Human)

PRO ID PR:P21462
DAG View
PRO Name fMet-Leu-Phe receptor (human)
Definition An fMet-Leu-Phe receptor that is encoded in the genome of human.
Short Label hFPR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21462 (FPR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y22 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
S328 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD   phospho.ELM   PhosphoSitePlus 7836371
T329 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD   phospho.ELM   PhosphoSitePlus 7836371
T331 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD   phospho.ELM   PhosphoSitePlus 7836371
S332 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD   phospho.ELM   PhosphoSitePlus 7836371
T334 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD   phospho.ELM   PhosphoSitePlus 7836371
T336 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD   phospho.ELM   PhosphoSitePlus 7836371
S338 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD   phospho.ELM   PhosphoSitePlus 7836371
T339 Phosphorylation A0A0S2Z3I6 (ADRBK1) HPRD   phospho.ELM   PhosphoSitePlus 7836371
S342 Phosphorylation Q16539 (MAPK14) neXtProt   PhosphoSitePlus   RLIMS-P 22447027


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P21462 (FPR1) S342 P25098 (GRK2) inhibited_association eFIP 22447027


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S211 R211 Biomuta DOID:1324 / lung cancer [ cosmic ]
S215 F215 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S328 A328 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S342 Y342 Biomuta DOID:363 / uterine cancer [ tcga ]