Protein Information

Cytoscape View


UniProt AC / UniProt ID P20273 / CD22_HUMAN
Protein Name B-cell receptor CD22 precursor
Gene Name Name: CD22
Synonyms:SIGLEC2;
Organism Homo sapiens (Human)

PRO ID PR:P20273
DAG View
PRO Name B-cell receptor CD22 (human)
Definition A B-cell receptor CD22 that is encoded in the genome of human.
Short Label hCD22
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20273 (CD22) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K288 Sumoylation PhosphoSitePlus
Y591 Phosphorylation PhosphoSitePlus
T715 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
Y762 Phosphorylation PRO   PhosphoSitePlus   RLIMS-P 16393971
Y796 Phosphorylation PhosphoSitePlus
K801 Ubiquitination PhosphoSitePlus
Y807 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 16393971, 27125377
Y822 Phosphorylation PRO   PhosphoSitePlus   RLIMS-P 16393971, 27125377
Y842 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 16393971


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046622 (hCD22/SigPep-/Phos:1) pY762,pY807,pY822 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S717 N717 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]