Protein Information

Cytoscape View

UniProt AC / UniProt ID P20248 / CCNA2_HUMAN
Protein Name Cyclin-A2
Gene Name Name: CCNA2
Organism Homo sapiens (Human)

PRO ID PR:P20248
DAG View
PRO Name cyclin-A2 (human)
Definition A cyclin-A2 that is encoded in the genome of human.
Short Label hCCNA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P20248 (CCNA2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
M1 Acetylation UniProt 19369195
S5 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19369195, 23186163, 18691976
K37 Ubiquitination PhosphoSitePlus
K54 Acetylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus   UniProt 19369195
K68 Acetylation PhosphoSitePlus
K76 Acetylation PhosphoSitePlus
K95 Acetylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K112 Acetylation PhosphoSitePlus
Y146 Phosphorylation HPRD 18691976
S151 Phosphorylation HPRD 18691976
S154 Phosphorylation P24941 (CDK2) PhosphoSitePlus   RLIMS-P   Signor 10652300
K192 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
T380 Phosphorylation RLIMS-P 10652300
K388 Ubiquitination PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus

P20248 (CCNA2) as PTM Enzyme

Substrate Site Score Source PMID
P62324 (BTG1) T158 HPRD 9820826


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046601 (hCCNA2/UbiqLys+) ub PRO

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P06493 (CDK1) Y15 P20248 (CCNA2) decreased_association eFIP 25664647

Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000025750 (hCDKN1B/iso:1/Phos:2) Interaction PR:P20248 (hCCNA2) PRO 17254966