iPTMnet Report for P17813 (ENG)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P17813 / EGLN_HUMAN
Protein Name Endoglin precursor
Gene Name Name: ENG
Synonyms:END;
Organism Homo sapiens (Human)

PRO ID PR:P17813
DAG View
PRO Name endoglin (human)
Definition An endoglin that is encoded in the genome of human.
Short Label hENG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17813 (ENG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N134 N-Glycosylation GlyGen   UniProt 19159218
T336 O-Glycosylation GlyGen 30459171
S337 O-Glycosylation GlyGen 30459171
T343 O-Glycosylation GlyGen 30459171
T344 O-Glycosylation GlyGen 30459171
Y612 Phosphorylation PhosphoSitePlus
Y614 Phosphorylation PhosphoSitePlus
S634 Phosphorylation P37173 (TGFBR2) neXtProt   PhosphoSitePlus   RLIMS-P 16785228
S635 Phosphorylation P37173 (TGFBR2) neXtProt   PhosphoSitePlus   RLIMS-P 16785228
T640 Phosphorylation P37023 (ACVRL1) PhosphoSitePlus 16785228
S646 Phosphorylation P37023 (ACVRL1) , P36897 (TGFBR1) neXtProt   PhosphoSitePlus 20042635
S649 Phosphorylation P36897 (TGFBR1) , P37023 (ACVRL1) neXtProt   PhosphoSitePlus 20042635
T650 Phosphorylation PhosphoSitePlus
T654 Phosphorylation P37023 (ACVRL1) PhosphoSitePlus 16785228


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N134 K134 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]