iPTMnet Report for P17813 (ENG)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P17813 / EGLN_HUMAN
Protein Name Endoglin precursor
Gene Name Name: ENG
Synonyms:END;
Organism Homo sapiens (Human)

PRO ID PR:P17813
DAG View
PRO Name endoglin (human)
Definition An endoglin that is encoded in the genome of human.
Short Label hENG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17813 (ENG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N134 N-Glycosylation GlyGen   UniProt 19159218
T336 O-Glycosylation GlyGen 30459171
S337 O-Glycosylation GlyGen 30459171
T343 O-Glycosylation GlyGen 30459171
T344 O-Glycosylation GlyGen 30459171
Y612 Phosphorylation PhosphoSitePlus
Y614 Phosphorylation PhosphoSitePlus
S634 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P 16785228
S634 Phosphorylation P37173 (TGFBR2) neXtProt   PhosphoSitePlus 16785228
S635 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P 16785228
S635 Phosphorylation P37173 (TGFBR2) neXtProt   PhosphoSitePlus 16785228
T640 Phosphorylation PhosphoSitePlus 16785228
T640 Phosphorylation P37023 (ACVRL1) PhosphoSitePlus 16785228
S646 Phosphorylation neXtProt   PhosphoSitePlus 20042635
S646 Phosphorylation P36897 (TGFBR1) neXtProt   PhosphoSitePlus 20042635
S646 Phosphorylation P37023 (ACVRL1) PhosphoSitePlus 20042635
S649 Phosphorylation neXtProt   PhosphoSitePlus 20042635
S649 Phosphorylation P36897 (TGFBR1) neXtProt   PhosphoSitePlus 20042635
S649 Phosphorylation P37023 (ACVRL1) PhosphoSitePlus 20042635
T650 Phosphorylation PhosphoSitePlus
T654 Phosphorylation PhosphoSitePlus 16785228
T654 Phosphorylation P37023 (ACVRL1) PhosphoSitePlus 16785228


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N134 K134 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]