iPTMnet Report for P17735 (TAT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P17735 / ATTY_HUMAN
Protein Name Tyrosine aminotransferase
Gene Name Name: TAT
Organism Homo sapiens (Human)

PRO ID PR:P17735
DAG View
PRO Name tyrosine aminotransferase (human)
Definition A tyrosine aminotransferase that is encoded in the genome of human.
Short Label hTAT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17735 (TAT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S16 Phosphorylation RLIMS-P 17083724, 29792216
K33 Acetylation PhosphoSitePlus
S46 Phosphorylation RLIMS-P 17083724, 29792216, 8914829
T321 Phosphorylation PhosphoSitePlus
Y442 Phosphorylation PhosphoSitePlus
S448 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 24275569


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P17735 (TAT) S16 O60563 (CCNT1) decreased_association eFIP 29792216
Phosphorylation P17735 (TAT) S16 P50750 (CDK9) unknown eFIP 29792216


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 L16 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T321 I321 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]