iPTMnet Report for P16870 (CPE)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P16870 / CBPE_HUMAN
Protein Name Carboxypeptidase E precursor
Gene Name Name: CPE
Organism Homo sapiens (Human)

PRO ID PR:P16870
DAG View
PRO Name carboxypeptidase E (human)
Definition A carboxypeptidase E that is encoded in the genome of human.
Short Label hCPE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16870 (CPE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N139 N-Glycosylation GlyGen 29741879, 26791533
K164 Ubiquitination PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
Y368 Phosphorylation PhosphoSitePlus
N390 N-Glycosylation GlyGen 26791533
T392 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
T403 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
Y428 Phosphorylation PhosphoSitePlus
T432 Phosphorylation PhosphoSitePlus
K433 Methylation PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N139 N-Glycosylation PRO 26791533
N390 N-Glycosylation PRO 26791533


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K173 R173 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S364 F364 Biomuta DOID:4159 / skin cancer [ cosmic ]
S404 F404 Biomuta DOID:4159 / skin cancer [ cosmic ]
T422 A422 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]