iPTMnet Report for P16870 (CPE)
Protein Information
UniProt AC / UniProt ID | P16870 / CBPE_HUMAN |
Protein Name | Carboxypeptidase E precursor |
Gene Name | Name: CPE |
Organism | Homo sapiens (Human) |
PRO ID | PR:P16870 |
PRO Name | carboxypeptidase E (human) |
Definition | A carboxypeptidase E that is encoded in the genome of human. |
Short Label | hCPE |
Category | organism-gene |
P16870 (CPE) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N139 | N-Glycosylation | score1 | GlyGen | 29741879, 26791533 | ||
K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
K203 | Ubiquitination | score1 | PhosphoSitePlus | |||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y368 | Phosphorylation | score1 | PhosphoSitePlus | |||
N390 | N-Glycosylation | score1 | GlyGen | 26791533 | ||
T392 | Phosphorylation | score1 | PhosphoSitePlus | |||
S394 | Phosphorylation | score1 | PhosphoSitePlus | |||
T403 | Phosphorylation | score1 | PhosphoSitePlus | |||
S404 | Phosphorylation | score1 | PhosphoSitePlus | |||
K406 | Ubiquitination | score1 | PhosphoSitePlus | |||
T422 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y428 | Phosphorylation | score1 | PhosphoSitePlus | |||
T432 | Phosphorylation | score1 | PhosphoSitePlus | |||
K433 | Methylation | score1 | PhosphoSitePlus | |||
K433 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K173 | R173 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
S364 | F364 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S404 | F404 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T422 | A422 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |