iPTMnet Report for P15428 (HPGD)
Protein Information
| UniProt AC / UniProt ID | P15428 / PGDH_HUMAN |
| Protein Name | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
| Gene Name | Name: HPGD Synonyms:PGDH1,SDR36C1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P15428 |
| PRO Name | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (human) |
| Definition | A 15-hydroxyprostaglandin dehydrogenase [NAD(+)] that is encoded in the genome of human. |
| Short Label | hHPGD |
| Category | organism-gene |
DAG ViewP15428 (HPGD) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S110 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y203 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K249 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y256 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T258 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T259 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K264 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K249 | R249 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
