iPTMnet Report for P15428 (HPGD)
Protein Information
UniProt AC / UniProt ID | P15428 / PGDH_HUMAN |
Protein Name | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
Gene Name | Name: HPGD Synonyms:PGDH1,SDR36C1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P15428 |
PRO Name | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (human) |
Definition | A 15-hydroxyprostaglandin dehydrogenase [NAD(+)] that is encoded in the genome of human. |
Short Label | hHPGD |
Category | organism-gene |
P15428 (HPGD) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
S110 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y203 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y206 | Phosphorylation | score1 | PhosphoSitePlus | |||
K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
K249 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y256 | Phosphorylation | score1 | PhosphoSitePlus | |||
T258 | Phosphorylation | score1 | PhosphoSitePlus | |||
T259 | Phosphorylation | score1 | PhosphoSitePlus | |||
K264 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K249 | R249 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |