iPTMnet Report for P12272 (PTHLH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P12272 / PTHR_HUMAN
Protein Name Parathyroid hormone-related protein precursor
Gene Name Name: PTHLH
Synonyms:PTHRP;
Organism Homo sapiens (Human)

PRO ID PR:P12272
DAG View
PRO Name parathyroid hormone-related protein (human)
Definition A parathyroid hormone-related protein that is encoded in the genome of human.
Short Label hPTHLH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12272 (PTHLH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
A70 Carboxylation IntAct 19674967
S85 Phosphorylation PhosphoSitePlus
T108 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T108 Phosphorylation P06493 (CDK1) phospho.ELM   PhosphoSitePlus 10373465
T113 Phosphorylation PhosphoSitePlus
T121 Phosphorylation P24941 (CDK2) , P06493 (CDK1) PhosphoSitePlus   Signor 10373465
T167 O-Glycosylation GlyGen 30459171
Site PTM Type PTM Enzyme Score Source PMID
T108 Phosphorylation P24941 (CDK2) HPRD 10373465
Site PTM Type PTM Enzyme Score Source PMID
T108 Phosphorylation P24941 (CDK2) HPRD 10373465


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S17 T17 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T113 M113 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T121 K121 Biomuta DOID:3571 / liver cancer [ cosmic ]
T167 K167 Biomuta DOID:4606 / bile duct cancer [ cosmic ]