iPTMnet Report for P12272 (PTHLH)
Protein Information
| UniProt AC / UniProt ID | P12272 / PTHR_HUMAN |
| Protein Name | Parathyroid hormone-related protein precursor |
| Gene Name | Name: PTHLH Synonyms:PTHRP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P12272 |
| PRO Name | parathyroid hormone-related protein (human) |
| Definition | A parathyroid hormone-related protein that is encoded in the genome of human. |
| Short Label | hPTHLH |
| Category | organism-gene |
DAG ViewP12272 (PTHLH) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| A70 | Carboxylation | score2 | IntAct | 19674967 | ||
| S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T108 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T108 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 10373465 | ||
| T108 | Phosphorylation | P06493 (CDK1) | score2 | phospho.ELM | 10373465 | |
| T113 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T121 | Phosphorylation | score3 | PhosphoSitePlus Signor | 10373465 | ||
| T121 | Phosphorylation | P06493 (CDK1) | score1 | Signor | 10373465 | |
| T121 | Phosphorylation | P24941 (CDK2) | score3 | PhosphoSitePlus Signor | 10373465 | |
| T167 | O-Glycosylation | score1 | GlyGen | 30459171 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S17 | T17 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| T113 | M113 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T121 | K121 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T167 | K167 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] |
