iPTMnet Report for P12109 (COL6A1)
Protein Information
UniProt AC / UniProt ID | P12109 / CO6A1_HUMAN |
Protein Name | Collagen alpha-1(VI) chain precursor |
Gene Name | Name: COL6A1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P12109 |
PRO Name | collagen alpha-1(VI) chain (human) |
Definition | A collagen alpha-1(VI) chain that is encoded in the genome of human. |
Short Label | hCOL6A1 |
Category | organism-gene |
P12109 (COL6A1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T104 | Phosphorylation | score1 | PhosphoSitePlus | |||
S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
K121 | Acetylation | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
K134 | Acetylation | score1 | PhosphoSitePlus | |||
Y152 | Phosphorylation | score1 | PhosphoSitePlus | |||
T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y165 | Phosphorylation | score1 | PhosphoSitePlus | |||
S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
N212 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19159218, ... | ||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
S348 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y477 | Phosphorylation | score1 | PhosphoSitePlus | |||
S486 | Phosphorylation | score1 | PhosphoSitePlus | |||
N516 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
Y527 | Phosphorylation | score1 | PhosphoSitePlus | |||
N537 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
Y542 | Phosphorylation | score1 | PhosphoSitePlus | |||
K688 | Ubiquitination | score1 | PhosphoSitePlus | |||
T701 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T703 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S746 | Phosphorylation | score1 | PhosphoSitePlus | |||
S766 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y793 | Phosphorylation | score1 | PhosphoSitePlus | |||
N804 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19159218, ... | ||
Y878 | Phosphorylation | score1 | PhosphoSitePlus | |||
N896 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
S1008 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S116 | N116 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
K121 | E121 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K134 | N134 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
S201 | I201 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S348 | L348 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
S486 | P486 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
Y527 | H527 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
N537 | K537 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |