iPTMnet Report for P12109 (COL6A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P12109 / CO6A1_HUMAN
Protein Name Collagen alpha-1(VI) chain precursor
Gene Name Name: COL6A1
Organism Homo sapiens (Human)

PRO ID PR:P12109
DAG View
PRO Name collagen alpha-1(VI) chain (human)
Definition A collagen alpha-1(VI) chain that is encoded in the genome of human.
Short Label hCOL6A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12109 (COL6A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T104 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
K121 Acetylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
N212 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K301 Ubiquitination PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
Y477 Phosphorylation PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
N516 N-Glycosylation GlyGen   UniProt 19159218
Y527 Phosphorylation PhosphoSitePlus
N537 N-Glycosylation GlyGen 23090970, 29741879, 24190977
Y542 Phosphorylation PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
T701 O-Glycosylation GlyGen 30459171
T703 O-Glycosylation GlyGen 30459171
S746 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
Y793 Phosphorylation PhosphoSitePlus
N804 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
Y878 Phosphorylation PhosphoSitePlus
N896 N-Glycosylation GlyGen   UniProt 19159218
S1008 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S116 N116 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K121 E121 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K134 N134 Biomuta DOID:1319 / brain cancer [ icgc ]
S201 I201 Biomuta DOID:3571 / liver cancer [ cosmic ]
S348 L348 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S486 P486 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y527 H527 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
N537 K537 Biomuta DOID:1324 / lung cancer [ cosmic ]