iPTMnet Report for P12035 (KRT3)
Protein Information
| UniProt AC / UniProt ID | P12035 / K2C3_HUMAN |
| Protein Name | Keratin, type II cytoskeletal 3 |
| Gene Name | Name: KRT3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P12035 |
| PRO Name | keratin, type II cytoskeletal 3 (human) |
| Definition | A keratin, type II cytoskeletal 3 that is encoded in the genome of human. |
| Short Label | hKRT3 |
| Category | organism-gene |
P12035 (KRT3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S65 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R84 | Methylation | score1 | PhosphoSitePlus | |||
| R113 | Methylation | score1 | PhosphoSitePlus | |||
| K203 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T204 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K208 | Acetylation | score1 | PhosphoSitePlus | |||
| K208 | Methylation | score1 | PhosphoSitePlus | |||
| K208 | Sumoylation | score1 | PhosphoSitePlus | |||
| K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K215 | Acetylation | score1 | PhosphoSitePlus | |||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S274 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y393 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T395 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T402 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y511 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y597 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S605 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S606 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S608 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S613 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S17 | F17 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S65 | N65 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S65 | I65 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| R84 | W84 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| R84 | Q84 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
| K215 | R215 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S274 | F274 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| Y511 | C511 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
DAG View