iPTMnet Report for P12035 (KRT3)
Protein Information
UniProt AC / UniProt ID | P12035 / K2C3_HUMAN |
Protein Name | Keratin, type II cytoskeletal 3 |
Gene Name | Name: KRT3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P12035 |
PRO Name | keratin, type II cytoskeletal 3 (human) |
Definition | A keratin, type II cytoskeletal 3 that is encoded in the genome of human. |
Short Label | hKRT3 |
Category | organism-gene |
P12035 (KRT3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
S65 | Phosphorylation | score1 | PhosphoSitePlus | |||
R84 | Methylation | score1 | PhosphoSitePlus | |||
R113 | Methylation | score1 | PhosphoSitePlus | |||
K203 | Ubiquitination | score1 | PhosphoSitePlus | |||
T204 | Phosphorylation | score1 | PhosphoSitePlus | |||
K208 | Acetylation | score1 | PhosphoSitePlus | |||
K208 | Methylation | score1 | PhosphoSitePlus | |||
K208 | Sumoylation | score1 | PhosphoSitePlus | |||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
K215 | Acetylation | score1 | PhosphoSitePlus | |||
K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
S274 | Phosphorylation | score1 | PhosphoSitePlus | |||
K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y393 | Phosphorylation | score1 | PhosphoSitePlus | |||
T395 | Phosphorylation | score1 | PhosphoSitePlus | |||
T402 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y511 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y597 | Phosphorylation | score1 | PhosphoSitePlus | |||
S605 | Phosphorylation | score1 | PhosphoSitePlus | |||
S606 | Phosphorylation | score1 | PhosphoSitePlus | |||
S608 | Phosphorylation | score1 | PhosphoSitePlus | |||
S613 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S17 | F17 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S65 | N65 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S65 | I65 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
R84 | W84 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
R84 | Q84 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
K215 | R215 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S274 | F274 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
Y511 | C511 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |