iPTMnet Report for P11712 (CYP2C9)
Protein Information
UniProt AC / UniProt ID | P11712 / CP2C9_HUMAN |
Protein Name | Cytochrome P450 2C9 |
Gene Name | Name: CYP2C9 Synonyms:CYP2C10; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P11712 |
PRO Name | cytochrome P450 2C9 (human) |
Definition | A cytochrome P450 2C9 that is encoded in the genome of human. |
Short Label | hCYP2C9 |
Category | organism-gene |
P11712 (CYP2C9) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
K200 | Acetylation | score1 | PhosphoSitePlus | |||
Y347 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y379 | Phosphorylation | score1 | PhosphoSitePlus | |||
S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
T392 | Phosphorylation | score1 | PhosphoSitePlus | |||
S393 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S127 | F127 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S390 | Y390 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S390 | F390 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] | |
T392 | I392 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T392 | N392 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
S393 | Y393 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
S393 | F393 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |