iPTMnet Report for P11473 (VDR)
Protein Information
| UniProt AC / UniProt ID | P11473 / VDR_HUMAN |
| Protein Name | Vitamin D3 receptor |
| Gene Name | Name: VDR Synonyms:NR1I1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P11473 |
| PRO Name | vitamin D3 receptor (human) |
| Definition | A vitamin D3 receptor that is encoded in the genome of human. |
| Short Label | hVDR |
| Category | organism-gene |
DAG ViewP11473 (VDR) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S51 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P+ RLIMS-P | 1656468, 14665442, 8392065 | ||
| S51 | Phosphorylation | P05771 (PRKCB) | score2 | RLIMS-P+ | 8392065 | |
| S51 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 1656468 | |
| T96 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S119 | Phosphorylation | score0 | RLIMS-P | 1656468 | ||
| K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S125 | Phosphorylation | score0 | RLIMS-P | 1656468 | ||
| S172 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T175 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S182 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus RLIMS-P | 15474498 | ||
| S182 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 15474498 | |
| S208 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P Signor | 17368182, 8384219, 8622969 | ||
| S208 | Phosphorylation | P68400 (CSNK2A1) | score4 | PhosphoSitePlus Signor | 17368182, 8622969 | |
| Y293 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K302 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y380 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S392 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K399 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S208 | Phosphorylation | score1 | HPRD | 8622969 | ||
| S208 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 8622969 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S13 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | P19793 (RXRA) | S260 | P11473 (VDR) | unknown | eFIP | 29300860 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S13 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S208 | I208 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S392 | T392 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| K399 | M399 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
