Protein Information

Cytoscape View

UniProt AC / UniProt ID P11473 / VDR_HUMAN
Protein Name Vitamin D3 receptor
Gene Name Name: VDR
Organism Homo sapiens (Human)

PRO ID PR:P11473
DAG View
PRO Name vitamin D3 receptor (human)
Definition A vitamin D3 receptor that is encoded in the genome of human.
Short Label hVDR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P11473 (VDR) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S51 Phosphorylation P17252 (PRKCA) , P05771 (PRKCB) PhosphoSitePlus   RLIMS-P+   RLIMS-P 1656468, 14665442, 8392065
T96 Phosphorylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
S119 Phosphorylation RLIMS-P 1656468
K123 Ubiquitination PhosphoSitePlus
S125 Phosphorylation RLIMS-P 1656468
S172 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
S182 Phosphorylation P17612 (PRKACA) phospho.ELM   PhosphoSitePlus   RLIMS-P 15474498
S208 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 17368182, 8384219, 8622969
Y293 Phosphorylation PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S208 Phosphorylation P68400 (CSNK2A1) HPRD 8622969
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P11473 (VDR) S208 Q15648 (MED1) increased_association eFIP 32990725

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S208 I208 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S392 T392 Biomuta DOID:3070 / malignant glioma [ cosmic ]
K399 M399 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]