iPTMnet Report for P11216 (PYGB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11216 / PYGB_HUMAN
Protein Name Glycogen phosphorylase, brain form
Gene Name Name: PYGB
Organism Homo sapiens (Human)

PRO ID PR:P11216
DAG View
PRO Name glycogen phosphorylase, brain form (human)
Definition A glycogen phosphorylase, brain form that is encoded in the genome of human.
Short Label hPYGB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11216 (PYGB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation PRO   UniProt 19413330, 22814378
K3 Acetylation PhosphoSitePlus
K3 Ubiquitination PhosphoSitePlus
T6 Phosphorylation HPRD   PhosphoSitePlus 20068231
S8 Phosphorylation PhosphoSitePlus
K10 Acetylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
S15 Phosphorylation Q8IWU2 (LMTK2) HPRD   phospho.ELM   PhosphoSitePlus 16887929, 17081983, 9362479
R29 Methylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
Y52 Phosphorylation PhosphoSitePlus
Y75 Phosphorylation PhosphoSitePlus
Y76 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
K81 Acetylation PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
Y162 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y186 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
Y197 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
Y204 Phosphorylation PhosphoSitePlus
T210 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
T241 Phosphorylation PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K316 Acetylation PhosphoSitePlus
C326 S-Nitrosylation dbSNO 26338901
K359 Ubiquitination PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
Y405 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K470 Ubiquitination PhosphoSitePlus
Y473 Phosphorylation PhosphoSitePlus
K479 Acetylation PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K520 Acetylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
K521 Acetylation PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
S527 Phosphorylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
Y554 Phosphorylation PhosphoSitePlus
K557 Ubiquitination PhosphoSitePlus
S562 Phosphorylation HPRD   PhosphoSitePlus 20068231
K575 Acetylation PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
Y614 Phosphorylation PhosphoSitePlus
K642 Ubiquitination PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
Y727 Phosphorylation PhosphoSitePlus
Y732 Phosphorylation PhosphoSitePlus
Y733 Phosphorylation PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
S752 Phosphorylation PhosphoSitePlus
K754 Ubiquitination PhosphoSitePlus
C784 Methylation IEDB 31844290
K796 Acetylation PhosphoSitePlus
K796 Ubiquitination PhosphoSitePlus
K811 Acetylation PhosphoSitePlus
K811 Ubiquitination PhosphoSitePlus
Y821 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000026215 (hPYGB/InitMet-/AcPyrdox:1) acA2 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 R8 Biomuta DOID:10283 / prostate cancer [ cosmic ]
Y52 C52 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y75 C75 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T210 S210 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
Y263 C263 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K316 N316 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T372 S372 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y473 N473 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K545 E545 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K557 N557 Biomuta DOID:363 / uterine cancer [ icgc ]
Y733 C733 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
C784 Y784 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y821 D821 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]