iPTMnet Report for P11216 (PYGB)
Protein Information
UniProt AC / UniProt ID | P11216 / PYGB_HUMAN |
Protein Name | Glycogen phosphorylase, brain form |
Gene Name | Name: PYGB |
Organism | Homo sapiens (Human) |
PRO ID | PR:P11216 |
PRO Name | glycogen phosphorylase, brain form (human) |
Definition | A glycogen phosphorylase, brain form that is encoded in the genome of human. |
Short Label | hPYGB |
Category | organism-gene |
P11216 (PYGB) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score2 | PRO UniProt | 19413330, 22814378 | ||
K3 | Acetylation | score1 | PhosphoSitePlus | |||
K3 | Ubiquitination | score1 | PhosphoSitePlus | |||
T6 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
K10 | Acetylation | score1 | PhosphoSitePlus | |||
K10 | Ubiquitination | score1 | PhosphoSitePlus | |||
S15 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus | 16887929, 17081983, 9362479 | ||
S15 | Phosphorylation | Q8IWU2 (LMTK2) | score2 | PhosphoSitePlus | 16887929 | |
R29 | Methylation | score1 | PhosphoSitePlus | |||
S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y52 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y76 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18083107 | ||
K81 | Acetylation | score1 | PhosphoSitePlus | |||
Y84 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y91 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y162 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y197 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18083107 | ||
Y204 | Phosphorylation | score1 | PhosphoSitePlus | |||
T210 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y227 | Phosphorylation | score1 | PhosphoSitePlus | |||
T229 | Phosphorylation | score1 | PhosphoSitePlus | |||
K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
T241 | Phosphorylation | score1 | PhosphoSitePlus | |||
K248 | Ubiquitination | score1 | PhosphoSitePlus | |||
K254 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y263 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y281 | Phosphorylation | score1 | PhosphoSitePlus | |||
K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
K316 | Acetylation | score1 | PhosphoSitePlus | |||
C326 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
T372 | Phosphorylation | score1 | PhosphoSitePlus | |||
K395 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y405 | Phosphorylation | score1 | PhosphoSitePlus | |||
S430 | Phosphorylation | score1 | PhosphoSitePlus | |||
K438 | Ubiquitination | score1 | PhosphoSitePlus | |||
K465 | Ubiquitination | score1 | PhosphoSitePlus | |||
K470 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y473 | Phosphorylation | score1 | PhosphoSitePlus | |||
K479 | Acetylation | score1 | PhosphoSitePlus | |||
K479 | Ubiquitination | score1 | PhosphoSitePlus | |||
K483 | Ubiquitination | score1 | PhosphoSitePlus | |||
K520 | Acetylation | score1 | PhosphoSitePlus | |||
K520 | Ubiquitination | score1 | PhosphoSitePlus | |||
K521 | Acetylation | score1 | PhosphoSitePlus | |||
K521 | Ubiquitination | score1 | PhosphoSitePlus | |||
S527 | Phosphorylation | score1 | PhosphoSitePlus | |||
K545 | Ubiquitination | score1 | PhosphoSitePlus | |||
K552 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y554 | Phosphorylation | score1 | PhosphoSitePlus | |||
K557 | Ubiquitination | score1 | PhosphoSitePlus | |||
S562 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K575 | Acetylation | score1 | PhosphoSitePlus | |||
K597 | Ubiquitination | score1 | PhosphoSitePlus | |||
K609 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y614 | Phosphorylation | score1 | PhosphoSitePlus | |||
K642 | Ubiquitination | score1 | PhosphoSitePlus | |||
K656 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y727 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y732 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y733 | Phosphorylation | score1 | PhosphoSitePlus | |||
K740 | Ubiquitination | score1 | PhosphoSitePlus | |||
S752 | Phosphorylation | score1 | PhosphoSitePlus | |||
K754 | Ubiquitination | score1 | PhosphoSitePlus | |||
C784 | Methylation | score1 | IEDB | 31844290 | ||
K796 | Acetylation | score1 | PhosphoSitePlus | |||
K796 | Ubiquitination | score1 | PhosphoSitePlus | |||
K811 | Acetylation | score1 | PhosphoSitePlus | |||
K811 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y821 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000026215 (hPYGB/InitMet-/AcPyrdox:1) | acA2 | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S8 | R8 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
Y52 | C52 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
Y75 | C75 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T210 | S210 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
Y263 | C263 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K316 | N316 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T372 | S372 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
Y473 | N473 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K545 | E545 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K557 | N557 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y733 | C733 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
C784 | Y784 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y821 | D821 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |