iPTMnet Report for P11086 (PNMT)
Protein Information
| UniProt AC / UniProt ID | P11086 / PNMT_HUMAN |
| Protein Name | Phenylethanolamine N-methyltransferase |
| Gene Name | Name: PNMT Synonyms:PENT; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P11086 |
| PRO Name | phenylethanolamine N-methyltransferase (human) |
| Definition | A phenylethanolamine N-methyltransferase that is encoded in the genome of human. |
| Short Label | hPNMT |
| Category | organism-gene |
DAG ViewP11086 (PNMT) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S7 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| Y35 | Phosphorylation | score0 | HPRD | 17322306 | ||
| Y40 | Phosphorylation | score0 | HPRD | 18767875 | ||
| Y248 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T255 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y256 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y248 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| Y248 | H248 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
