iPTMnet Report for P11086 (PNMT)
Protein Information
UniProt AC / UniProt ID | P11086 / PNMT_HUMAN |
Protein Name | Phenylethanolamine N-methyltransferase |
Gene Name | Name: PNMT Synonyms:PENT; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P11086 |
PRO Name | phenylethanolamine N-methyltransferase (human) |
Definition | A phenylethanolamine N-methyltransferase that is encoded in the genome of human. |
Short Label | hPNMT |
Category | organism-gene |
P11086 (PNMT) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S7 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y35 | Phosphorylation | score0 | HPRD | 17322306 | ||
Y40 | Phosphorylation | score0 | HPRD | 18767875 | ||
Y248 | Phosphorylation | score1 | PhosphoSitePlus | |||
T255 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y256 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y248 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
Y248 | H248 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |