iPTMnet Report for P0DMV9 (HSPA1B)
Protein Information
| UniProt AC / UniProt ID | P0DMV9 / HS71B_HUMAN |
| Protein Name | Heat shock 70 kDa protein 1B |
| Gene Name | Name: HSPA1B Synonyms:HSP72; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P0DMV9 |
| PRO Name | heat shock 70 kDa protein 1B (human) |
| Definition | A heat shock 70 kDa protein 1B that is encoded in the genome of human. |
| Short Label | hHSPA1B |
| Category | organism-gene |
P0DMV9 (HSPA1B) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330 | ||
| T66 | Phosphorylation | score0 | RLIMS-P | 25940345 | ||
| K77 | Acetylation | score2 | UniProt | 27708256 | ||
| K108 | Acetylation | score1 | UniProt | 19608861 | ||
| K246 | Acetylation | score1 | UniProt | 19608861 | ||
| K348 | Acetylation | score1 | UniProt | 19608861 | ||
| N417 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| T425 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
| S432 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
| R469 | Methylation | score1 | UniProt | 24129315 | ||
| K561 | Methylation | score1 | UniProt | 24129315 | ||
| S631 | Phosphorylation | score1 | UniProt | 20068231 | ||
| S633 | Phosphorylation | score1 | UniProt | 20068231 | ||
| T636 | Phosphorylation | score1 | UniProt | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| A2 | V2 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S631 | C631 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T636 | N636 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |
DAG View