iPTMnet Report for P0DMV9 (HSPA1B)
Protein Information
UniProt AC / UniProt ID | P0DMV9 / HS71B_HUMAN |
Protein Name | Heat shock 70 kDa protein 1B |
Gene Name | Name: HSPA1B Synonyms:HSP72; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P0DMV9 |
PRO Name | heat shock 70 kDa protein 1B (human) |
Definition | A heat shock 70 kDa protein 1B that is encoded in the genome of human. |
Short Label | hHSPA1B |
Category | organism-gene |
P0DMV9 (HSPA1B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330 | ||
T66 | Phosphorylation | score0 | RLIMS-P | 25940345 | ||
K77 | Acetylation | score2 | UniProt | 27708256 | ||
K108 | Acetylation | score1 | UniProt | 19608861 | ||
K246 | Acetylation | score1 | UniProt | 19608861 | ||
K348 | Acetylation | score1 | UniProt | 19608861 | ||
N417 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
T425 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
S432 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
R469 | Methylation | score1 | UniProt | 24129315 | ||
K561 | Methylation | score1 | UniProt | 24129315 | ||
S631 | Phosphorylation | score1 | UniProt | 20068231 | ||
S633 | Phosphorylation | score1 | UniProt | 20068231 | ||
T636 | Phosphorylation | score1 | UniProt | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | V2 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S631 | C631 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T636 | N636 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |