iPTMnet Report for P09693 (CD3G)
Protein Information
| UniProt AC / UniProt ID | P09693 / CD3G_HUMAN |
| Protein Name | T-cell surface glycoprotein CD3 gamma chain precursor |
| Gene Name | Name: CD3G Synonyms:T3G; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P09693 |
| PRO Name | T-cell surface glycoprotein CD3 gamma chain (human) |
| Definition | A CD3 gamma that is encoded in the genome of human. |
| Short Label | hCD3G |
| Category | organism-gene |
P09693 (CD3G) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K32 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N52 | N-Glycosylation | score3 | GlyGen UniProt | 8636209 | ||
| K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K60 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K71 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N92 | N-Glycosylation | score3 | GlyGen UniProt | 8636209 | ||
| K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S145 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 2540970, 3112151 | ||
| S148 | Phosphorylation | P17252 (PRKCA) | score4 | phospho.ELM PhosphoSitePlus UniProt | 8187769, 2540970, 3112151 | |
| K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y160 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 16094384 | ||
| K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y171 | Phosphorylation | score2 | HPRD IEDB phospho.ELM PhosphoSitePlus | 35494241, 16094384 | ||
| S172 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000025780 (hCD3G/iso:1/SigPep-/Phos:1) | pY160,pY171 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K32 | N32 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K60 | N60 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K79 | R79 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
| K79 | N79 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S145 | P145 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S148 | P148 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K150 | N150 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| Y171 | H171 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
DAG View