Protein Information

Cytoscape View


UniProt AC / UniProt ID P09693 / CD3G_HUMAN
Protein Name T-cell surface glycoprotein CD3 gamma chain precursor
Gene Name Name: CD3G
Synonyms:T3G;
Organism Homo sapiens (Human)

PRO ID PR:P09693
DAG View
PRO Name T-cell surface glycoprotein CD3 gamma chain (human)
Definition A CD3 gamma that is encoded in the genome of human.
Short Label hCD3G
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09693 (CD3G) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K32 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
N52 N-Glycosylation GlyGen   UniProt 8636209
K57 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
N92 N-Glycosylation GlyGen   UniProt 8636209
K95 Ubiquitination PhosphoSitePlus
S145 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 2540970, 3112151
S148 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 8187769, 2540970, 3112151
S148 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 8187769
K150 Ubiquitination PhosphoSitePlus
Y160 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16094384
K164 Ubiquitination PhosphoSitePlus
Y171 Phosphorylation HPRD   IEDB   phospho.ELM   PhosphoSitePlus 35494241, 16094384
S172 Phosphorylation IEDB   PhosphoSitePlus 35494241
Site PTM Type PTM Enzyme Score Source PMID
Y160 Phosphorylation PRO
Y171 Phosphorylation PRO


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000025780 (hCD3G/iso:1/SigPep-/Phos:1) pY160,pY171 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K32 N32 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K60 N60 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K79 R79 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K79 N79 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S145 P145 Biomuta DOID:1324 / lung cancer [ cosmic ]
S148 P148 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K150 N150 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y171 H171 Biomuta DOID:3571 / liver cancer [ cosmic ]