iPTMnet Report for P09038 (FGF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09038 / FGF2_HUMAN
Protein Name Fibroblast growth factor 2 precursor
Gene Name Name: FGF2
Synonyms:FGFB;
Organism Homo sapiens (Human)

PRO ID PR:P09038
DAG View
PRO Name fibroblast growth factor 2 (human)
Definition A fibroblast growth factor 2 that is encoded in the genome of human.
Short Label hFGF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09038 (FGF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S62 Phosphorylation PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
R82 Methylation PhosphoSitePlus
R84 Methylation PhosphoSitePlus
R86 Methylation PhosphoSitePlus
R96 Methylation PhosphoSitePlus
R98 Methylation PhosphoSitePlus
R108 Methylation PhosphoSitePlus
R110 Methylation PhosphoSitePlus
R112 Methylation PhosphoSitePlus
R118 Methylation PhosphoSitePlus
R124 Methylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
T141 Phosphorylation PhosphoSitePlus
K168 Acetylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation P42680 (TEC) neXtProt   UniProt 20230531
K228 Sumoylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
Y253 Phosphorylation PhosphoSitePlus
T254 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus 2541433
Y257 Phosphorylation P42680 (TEC) neXtProt 20230531
K261 Acetylation PhosphoSitePlus
K267 Acetylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K271 Acetylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K277 Acetylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y82 Phosphorylation PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S62 L62 Biomuta DOID:1612 / breast cancer [ icgc ]
Y82 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y124 H124 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y124 F124 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T141 A141 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S206 P206 Biomuta DOID:363 / uterine cancer [ icgc ]
Y215 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y257 F257 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y257 H257 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K277 T277 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S288 R288 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]