iPTMnet Report for P09038 (FGF2)
Protein Information
UniProt AC / UniProt ID | P09038 / FGF2_HUMAN |
Protein Name | Fibroblast growth factor 2 precursor |
Gene Name | Name: FGF2 Synonyms:FGFB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P09038 |
PRO Name | fibroblast growth factor 2 (human) |
Definition | A fibroblast growth factor 2 that is encoded in the genome of human. |
Short Label | hFGF2 |
Category | organism-gene |
P09038 (FGF2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
T65 | Phosphorylation | score1 | PhosphoSitePlus | |||
R82 | Methylation | score1 | PhosphoSitePlus | |||
R84 | Methylation | score1 | PhosphoSitePlus | |||
R86 | Methylation | score1 | PhosphoSitePlus | |||
R96 | Methylation | score1 | PhosphoSitePlus | |||
R98 | Methylation | score1 | PhosphoSitePlus | |||
R108 | Methylation | score1 | PhosphoSitePlus | |||
R110 | Methylation | score1 | PhosphoSitePlus | |||
R112 | Methylation | score1 | PhosphoSitePlus | |||
R118 | Methylation | score1 | PhosphoSitePlus | |||
R124 | Methylation | score1 | PhosphoSitePlus | |||
S138 | Phosphorylation | score1 | PhosphoSitePlus | |||
T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
K168 | Acetylation | score1 | PhosphoSitePlus | |||
S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y215 | Phosphorylation | score3 | neXtProt UniProt | 20230531 | ||
Y215 | Phosphorylation | P42680 (TEC) | score2 | neXtProt | 20230531 | |
K228 | Sumoylation | score1 | PhosphoSitePlus | |||
K228 | Ubiquitination | score1 | PhosphoSitePlus | |||
S242 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y245 | Phosphorylation | score1 | PhosphoSitePlus | |||
S250 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y253 | Phosphorylation | score1 | PhosphoSitePlus | |||
T254 | Phosphorylation | score3 | neXtProt PhosphoSitePlus | 2541433 | ||
T254 | Phosphorylation | P17612 (PRKACA) | score2 | neXtProt | 2541433 | |
Y257 | Phosphorylation | score2 | neXtProt | 20230531 | ||
Y257 | Phosphorylation | P42680 (TEC) | score2 | neXtProt | 20230531 | |
K261 | Acetylation | score1 | PhosphoSitePlus | |||
K267 | Acetylation | score1 | PhosphoSitePlus | |||
K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
K271 | Acetylation | score1 | PhosphoSitePlus | |||
K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
K277 | Acetylation | score1 | PhosphoSitePlus | |||
S285 | Phosphorylation | score1 | PhosphoSitePlus | |||
S288 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y82 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y112 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y124 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S62 | L62 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
Y82 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y124 | H124 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y124 | F124 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T141 | A141 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S206 | P206 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y215 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y257 | F257 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y257 | H257 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K277 | T277 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S288 | R288 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |